Effect of acute and chronic pain on reproductive functions in female rats

In this work, 30 adult female rats were used to study the effect of acute and chronic pain on the reproductive functions. Rats were divided into three equal groups, i.e. control group, acute pain group [exposed to pain once for one hour] and chronic pain group [exposed to pain one hour daily for two weeks]. In each group, gonadotropines and sex hormones were measured .The uterus and ovaries of each group were examined microscopically for histopathological changes. The results showed that acute pain led to an increase in gonadotropines and sex hormones levels as well as histological changes in the uterus [some dilatation in the uterine lumen, decreased uterine vascularity and increased polymorph-nuclear leucocytes [PNL] infiltration and stromal cellularity] and the ovaries [increased number and viability of corpora lutea] The chronic pain led to an increase in FSH, and decrease in LH and sex hormones with, histological changes in the uterus [dilated uterine lumen with increased vascularity, PNL infiltration and stromal cellularity] and the ovary [viable corpora lutea disappeared and only regressive ones were found]. The results of this study showed that pain as a physiological stressor has negative effects on reproductive functions as it causes disturbances in the harmony of gonadotropines and sex hormones and their effects on target tissues

Effect of chromium deficiency and supplementation on some aspects of carbohydrate and lipid metabolism in male albino rats

In this work, thirty adult male albino rats were used to study the effect of chromium deficiency and supplementation on carbohydrates and lipid metabolism. Rats were divided into three equal groups control, chromium deficient and chromium supplemented. Rats of the first group were fed on normal diet, rats of the second group were fed on a chromium deficient diet. Rats of the third group were fed on the same chromium deficient diet but were supplemented with oral chromium picolinate [90 |-l micro gm / kg body weight] daily for forty five days. At the end of the experimental period [45 days] plasma glucose, insulin serum triglycerides, cholesterol, LDL and HDL were determined. The study showed that chromium deficiency led to a significant increase in plasma glucose level, and insulin with insignificant changes in serum triglycerides, cholesterol, HDL and LDL as compared to control group. The study showed also that chromium supplementation led to an insignificant increase in serum glucose and insulin with significant decrease in serum triglycerides, cholesterol, LDL and a significant increase in serum HDL

Effect of boswellia carterii birdw on carbohydrate metabolism in diabetic male albino rats

In the current study, thirty male adult albino rats were used to investigate the effect of Boswellia Carterii Birdw [BCB] on carbohydrate metabolism in alloxan-induced diabetes. Rats were divided into three equal groups, control, diabetic non treated and diabetic BCB treated groups. After thirty days of treatment five rats of each group were sacrificed and the others were left without any additional treatment for another 15 days [recovery period] then were sacrificed. The body weight of each rat was determined at the beginning and the end of each period. Blood glucose, serum insulin and liver glycogen were determined for each rat at the end of each period. It was noticed that B.C.B treatment led to a significant improve in the decreased body weight, hyperglycemia, hypoinsulinemia, decreased liver glycogen caused by alloxan. And this improvement was also seen after the recovery period. B.C.B treatment led also to marked improvement in the histopathological degenerative changes in the beta cells of islets of Langerhans caused by alloxan after both the treated and recovery periods