Duodenal Obstruction and Acquired Gastroduodenal Fistula Caused by Magnets: A Case Report

Foreign body ingestion in children is commonly encountered and this usually resolves spontaneously. Single magnet ingestion usually does not need additional medical treatment. However, multiple magnets can attract each other in intestinal loops and several complications can develop such as bowel obstruction and fistula formation. In this situation, endoscopic and/or surgical intervention is inevitably required. Therefore, making the correct diagnosis is needed for cases of magnets ingestion, and this should be done as soon as possible for children. We report here on a case of gastroduodenal fistula and duodenal obstruction caused by the interaction of four magnets.

Various Ocular MR Imagings in a Mouse Implanted with a New Cell Line of Retinoblastoma and the Correlation with the Pathology: Preliminary Study

PURPOSE: We wanted to show various MR and correlated pathologic images of retinoblastoma in nude mousewith a new human retinoblastom cell line (SNUOT-Rb1), which was inoculated into the intravitreous cavity. MATERIALS AND METHODS: The established cell line was inoculated into the intravitreous cavity of 36 eyeballs of 18 mice and the transplanted retinoblastoma was examined for 3 months. The T1-weighted (T1WI), T2-weighted (T2WI), and contrast enhanced (Gd-DTPA) T1-weighted images were obtained with using a small loop coil. After scanning, the mice's eyeballs were extracted and the hematoxylin & eosin stained specimens were examined with a microscope. We compared the MR imagings with pathologic findings and evaluated the character of the tumors. RESULTS: The innoculated cells in the eyeballs of the mice grew into retinoblastoma (23/36, 64%). The eyeballs with retinoblastoma protruded externally and showed focal hemorrhage. Most tumors showed iso-signal intensity on TIWI (13/23, 57%), high signal intensity on T2WI (17/23, 74%), and good enhancement (21/23, 91%) with contrast. Almost all of the tumors (n=21) were located in the retina and three extraretinal tumors were confirmed by pathology. Involvement of the optic nerve was suspected on MRI and this was confirmed by pathology in 6 cases and 5 cases, respectively. CONCLUSION: We could demonstrate various MR imagings of transplanted retinoblastoma by using the new tumor cell line in vivo.

Effect of irradiation on the healing of extraction sockets in diabetic rats / 대한구강악안면방사선학회지

PURPOSE: To observe the histologic pattern of healing in molar tooth extraction sockets of streptozotocin-induced diabetic rats following irradiation. MATERIALS AND METHODS: Mature Sprague-Dawley rats were divided into three groups: control, diabetic, and diabetic-irradiated groups. Diabetes mellitus was induced by injecting streptozotocin. Control rats were injected with a citrate buffer only. After 5 days, the right maxillary first molar was extracted under general anesthesia from each of the rats. After the extraction, rats in the diabetic-irradiated group were irradiated with a single absorbed dose of 10 Gy to the head and neck region. The rats were killed at 1, 3, 7, 14, 21, and 28 days after treatment. Tissue sections were stained with hematoxylineosin and Masson's trichrome. RESULTS: In the diabetic and diabetic-irradiated groups, the early healing process of the socket extraction was similar to the control group, but bone formation was delayed at 7 days after the treatment. In the diabetic-irradiated group, alveolar bone surrounding the extraction socket showed signs of necrosis at 3 days after treatment, and hemorrhage was observed in connective tissue within the extraction socket at 14 days after treatment. CONCLUSION: This experiment revealed that the healing process of the extraction socket was severely delayed and retarded by irradiation in the diabetic state.

The Effects of Irradiation and Calcium-deficient Diet on the Expression of Interleukin-1 during Tooth Formation of Rat Molar / 대한구강악안면방사선학회지

PURPOSE: To elucidate the effects of the irradiation and calcium-deficient diet on expression of interleukin(IL)-1 during tooth formation of rat molar MATERIALS AND METHODS: The pregnant three-week-old Spague-Dawley rats were used for the study. The control group was non-irradiation/normal diet group, and the experimental groups were irradiation/normal diet group and irradiation/calcium-diet group. The abdomen of the rats on the 9th day of pregnancy were irradiated with single dose of 350 cGy. The rat pups were sacrificed on the 14th day after delivery and the maxillae tooth germs were taken. The specimen were prepared to make sections for light microscopy, and some of tissue sections were stained immunohistochemically with anti-IL-1 antibody. RESULTS: In the irradiation/normal diet group, dental follicle showed fewer blood vessels, mononuclear cells, and fusions of mononuclear cells than in non-irradiation/normal diet group. Alveolar bone showed a few osteoblasts and osteoclasts. Periodontal ligament showed collagen fibers and fibroblasts with irregularity. Weak immunoreactivity for IL-1 was shown in dental follicle, alveolar bone, and periodontal ligament. In the irradiation/calcium-deficient diet group, dental follicle showed sparse cellularity. Alveolar bone showed diminished number of osteoblasts. Periodontal ligament showed irregular collagen fibers and atrophy of cementoblasts and fibroblasts. No immunoreactivity for IL-1 was shown in dental follicle, alveolar bone, and periodontal ligament. CONCLUSION: Irradiation and calcium-deficient diet seems to cause disturbance of the expression of interleukin-1 during tooth formation of rat molar.