Complete androgen blockade in advanced prostate cancer: a clinical experience

To evaluate the clinical and biochemical outcome of patients with advanced prostate cancer treated by complete androgen blockage [CAB]. A total number of thirty patients with histologically confirmed advance prostate cancer and serum PSA level of more than 30ng/ml were subjected to bilateral subcapsular orchidectomy, supplemented with oral antiandrogens. These patients were followed for a period of two years by recording their symptoms and serum PSA level at twelve weeks intervals. Only 16[53.33%] patients complied with the protocol of the study and observed two years followup. 12[75%] patients showed complete response to CAB while 4[25%] patients showed rising PSA levels and became symptomatic after one year of treatment. CAB is still the treatment of choice for patients with advanced prostate cancer

Tubeless and stentless pyeloplasty

The aim of this study was to study cases of ureteroplevic junction obstruction undergoing open pyeloplasties without any stents and tubes.The techniques of operations designed in the present study were 88 Anderson Hyne's peyeloplasties, 22 Foley Y-V Plasty, 24 Culp, Deweered and the rest of the 16 cases Scardino- Prince flap pyeloplasties. 142 [95%] of cases had improvement in symptoms and renal functions while there was failure in 8[5%] of cases. It is concluded that stents and nehrostomy tubes are not needed in patients except in those undergoing secondary repairs or having inflammation