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1.
Anesthesia and Pain Medicine ; : 335-340, 2019.
Artigo em Inglês | WPRIM | ID: wpr-762267

RESUMO

BACKGROUND: Spontaneous intracranial hypotension (SIH) is a condition caused by spontaneous leakage of cerebrospinal fluid, with postural headache as the primary symptom. Orthostatic headache caused by SIH is often not resolved by conservative management. CASE: We performed 15 epidural blood patch treatments in a 43-year-old female patient; however, they were only transiently effective. To improve the patient's SIH and orthostatic headache, epidural fibrin glue patch treatment was attempted. Fibrin glue is a substance that can act as a bio-friendly adhesive by facilitating the coagulation cascade. In our case, 3 epidural fibrin glue patch treatments were performed and the symptoms completely resolved. CONCLUSIONS: The epidural fibrin glue patch may be beneficial for the treatment of refractory postural headaches caused by SIH.


Assuntos
Adulto , Feminino , Humanos , Adesivos , Placa de Sangue Epidural , Líquido Cefalorraquidiano , Adesivo Tecidual de Fibrina , Fibrina , Cefaleia , Hipotensão Intracraniana
2.
Anesthesia and Pain Medicine ; : 85-90, 2019.
Artigo em Inglês | WPRIM | ID: wpr-719398

RESUMO

A 65-year-old male patient underwent C-arm fluoroscopy-guided bilateral celiac plexus neurolysis to relieve peritoneal seeding-related pain associated with pancreatic cancer. Following confirmation of spreading, and no intravascular injection of contrast media, 7.5 ml of 0.25% chirocaine was injected in each side. The pain subsided after the block, with no motor or sensory deficits. Subsequently, celiac plexus neurolysis with 99.8% alcohol was performed using a posterolateral approach under fluoroscopic guidance. The patient was instructed to maintain a prone position for 2 hours while the procedure was performed. Approximately 4 hours later, the patient experienced paralysis of both lower extremities and hypoesthesia. Emergent magnetic resonance imaging of the thoracic and lumbar spine revealed gray matter signal change in the cord and conus medullaris at the T10-L1 level, and decreased perfusion at the T11-T12 vertebral bodies, suggesting spinal cord infarction. The patient remained paraplegic until his death 24 days later.


Assuntos
Idoso , Humanos , Masculino , Plexo Celíaco , Meios de Contraste , Substância Cinzenta , Hipestesia , Infarto , Extremidade Inferior , Imageamento por Ressonância Magnética , Neoplasias Pancreáticas , Paralisia , Paraplegia , Perfusão , Decúbito Ventral , Medula Espinal , Coluna Vertebral
3.
The Korean Journal of Pain ; : 244-252, 2018.
Artigo em Inglês | WPRIM | ID: wpr-742201

RESUMO

C-arm fluoroscopy is useful equipment in interventional pain management because it helps to guide correct needle targeting for the accurate injection and drug delivery. However, due to increased use of C-arm fluoroscopy in various pain procedures, the risk of radiation exposure is a significant concern for pain physicians. The harmful biological effects of ionizing radiation on the human body are well known. It is therefore necessary to strive to reduce radiation exposure. Lead aprons with thyroid shields are the most fundamental radiation protective devices for interventional procedures, and are very effective. However, the operator's radiation safety cannot be guaranteed because pain physicians seem to lack sufficient interest, knowledge, and awareness about radiation safety. Also, inappropriate care and use of radiation protective devices may result in a higher risk of radiation exposure. The purpose of this article was to review the literature on radiation safety with a focus on lead aprons and thyroid shields and present recommendations related to those devices during C-arm fluoroscopic-guided interventions by pain physicians.


Assuntos
Fluoroscopia , Corpo Humano , Agulhas , Manejo da Dor , Equipamentos de Proteção , Exposição à Radiação , Proteção Radiológica , Radiação Ionizante , Glândula Tireoide
4.
Korean Journal of Anesthesiology ; : 337-342, 2012.
Artigo em Inglês | WPRIM | ID: wpr-26357

RESUMO

BACKGROUND: Third-generation hydroxyethyl starch (HES) solutions have been developed to minimize negative effects on hemostasis. In normal pregnancy, the coagulation activity increases, reaching a maximum around term. This study examined the effects of hemodilution with HES 130/0.4 (6%) on blood coagulation in parturients in vivo and in vitro. METHODS: Forty parturients scheduled for cesarean sections were assigned randomly to receive either 500 or 1,000 ml of HES 130/0.4 (6%). Rotation thromboelastometry (ROTEM(R)) measurements were performed before and after administering HES 130/0.4 (6%). In addition, blood samples obtained from 20 randomly selected parturients were diluted 10% to 40% using HES 130/0.4 (6%), and ROTEM(R) measurements were performed before and after dilution. The changes from baseline and the effects of dilution were analyzed by ROTEM(R) parameters. RESULTS: Infusions of 500 or 1,000 ml of HES 130/0.4 (6%) in the parturients altered the clot formation time, alpha angle, and maximal clot firmness, although all remained within normal ranges. HES 130/0.4 (6%) affected in vitro blood coagulation in parturients' blood containing 10, 20, 30, and 40% HES. The clotting time was prolonged at each dilution percentage, but remained within the normal range. Other parameters showed an impairment of the coagulation system. CONCLUSIONS: Blood coagulation in parturients may be compromised at high dilution ratios of HES 130/0.4 (6%) to blood. Nevertheless, the infusion of 1,000 ml of HES 130/0.4 (6%) in normal parturients did not significantly affect blood coagulation.


Assuntos
Feminino , Gravidez , Coagulação Sanguínea , Cesárea , Hemodiluição , Hemostasia , Derivados de Hidroxietil Amido , Valores de Referência
5.
The Korean Journal of Pain ; : 199-204, 2011.
Artigo em Inglês | WPRIM | ID: wpr-107269

RESUMO

BACKGROUND: Although many clinicians know about the reducing effects of the pulsed and low-dose modes for fluoroscopic radiation when performing interventional procedures, few studies have quantified the reduction of radiation-absorbed doses (RADs). The aim of this study is to compare how much the RADs from a fluoroscopy are reduced according to the C-arm fluoroscopic modes used. METHODS: We measured the RADs in the C-arm fluoroscopic modes including 'conventional mode', 'pulsed mode', 'low-dose mode', and 'pulsed + low-dose mode'. Clinical imaging conditions were simulated using a lead apron instead of a patient. According to each mode, one experimenter radiographed the lead apron, which was on the table, consecutively 5 times on the AP views. We regarded this as one set and a total of 10 sets were done according to each mode. Cumulative exposure time, RADs, peak X-ray energy, and current, which were viewed on the monitor, were recorded. RESULTS: Pulsed, low-dose, and pulsed + low-dose modes showed significantly decreased RADs by 32%, 57%, and 83% compared to the conventional mode. The mean cumulative exposure time was significantly lower in the pulsed and pulsed + low-dose modes than in the conventional mode. All modes had pretty much the same peak X-ray energy. The mean current was significantly lower in the low-dose and pulsed + low-dose modes than in the conventional mode. CONCLUSIONS: The use of the pulsed and low-dose modes together significantly reduced the RADs compared to the conventional mode. Therefore, the proper use of the fluoroscopy and its C-arm modes will reduce the radiation exposure of patients and clinicians.


Assuntos
Humanos , Fluoroscopia , Compostos Organotiofosforados , Doses de Radiação , Intensificação de Imagem Radiográfica
6.
Korean Journal of Anesthesiology ; : 210-215, 2011.
Artigo em Inglês | WPRIM | ID: wpr-229280

RESUMO

BACKGROUND: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Magnesium has been reported to be effective in reducing the incidence or prophylaxis of AF. Magnesium is also an essential constituent of many enzyme systems and plays a physiological role in coagulation regulation. The aim of the present study was to examine the effects of magnesium, whether magnesium infusion might decrease the incidence of AF and induce hypocoagulable state in patients with AF, who were undergoing mitral valve annuloplasty. METHODS: This prospective laboratory study was performed using blood from patients with AF undergoing mitral valve annuloplasty. The radial artery was punctured with a 20 gauge catheter and used for monitoring continuous arterial pressure and blood sampling. After anesthesia induction, 4 g of magnesium was mixed with 100 ml normal saline and infused for 5 minutes. Magnesium, calcium, activated clotting time (ACT) and thromboelastographic parameters were checked before and 60 minutes after the magnesium infusion. The electrocardiography changes after magnesium infusion were also checked before commencing cardiopulmonary bypass. RESULTS: After magnesium infusion, the serum level of magnesium increased significantly but serum calcium did not change significantly. ACT did not change significantly before or after magnesium infusion. The thromboelastographic parameters showed no significant changes before or after magnesium infusion. None of the patients converted to sinus rhythm from AF after the magnesium infusion. CONCLUSIONS: A magnesium infusion did not influence the course of AF and coagulation in patients during prebypass period with AF undergoing mitral valve annuloplasty.


Assuntos
Humanos , Anestesia , Arritmias Cardíacas , Pressão Arterial , Fibrilação Atrial , Cálcio , Ponte Cardiopulmonar , Catéteres , Eletrocardiografia , Incidência , Magnésio , Valva Mitral , Anuloplastia da Valva Mitral , Estudos Prospectivos , Artéria Radial , Tromboelastografia
7.
Anesthesia and Pain Medicine ; : 155-158, 2010.
Artigo em Inglês | WPRIM | ID: wpr-193391

RESUMO

Acute fatty liver of pregnancy is a rare but usually fatal complication of the third trimester. We report the case of a 28-year-old primigravida at 37 weeks of gestation with an acute fatty liver. Continuous fetal heart rate monitoring demonstrated frequent late fetal heart decelerations and the lack of beat-to-beat variability during the induction of vaginal delivery. We decided to perform an emergency cesarean section under a combined general-epidural anesthesia with bispectral index. No complications occurred during or after surgery except for a delayed recovery from the muscle relaxant. The patient made an uneventful recovery and discharged at eight days after cesarean section.


Assuntos
Adulto , Feminino , Humanos , Gravidez , Anestesia , Cesárea , Desaceleração , Emergências , Fígado Gorduroso , Coração Fetal , Frequência Cardíaca Fetal , Músculos , Complicações na Gravidez , Terceiro Trimestre da Gravidez
8.
Korean Journal of Anesthesiology ; : 371-375, 2009.
Artigo em Coreano | WPRIM | ID: wpr-189216

RESUMO

Loeys-Dietz Syndrome (LDS) is a recently described autosomal dominant aortic aneurysm syndrome with widespread systemic involvement. It is characterized by the triad of 1) arterial tortuosity and aneurysms, 2) hypertelorism, and 3) bifid uvula or cleft palate. A 12-year-old boy with LDS was scheduled to undergo correction of aortic valve regurgitation due to aortic annuloectasia. We report our clinical experiences of a case of LDS patient with brief review of related literatures and relevant anesthetic problems.


Assuntos
Criança , Humanos , Aneurisma , Aneurisma Aórtico , Valva Aórtica , Artérias , Fissura Palatina , Hipertelorismo , Instabilidade Articular , Síndrome de Loeys-Dietz , Dermatopatias Genéticas , Úvula , Malformações Vasculares
9.
Korean Journal of Anesthesiology ; : 102-108, 2008.
Artigo em Coreano | WPRIM | ID: wpr-181756

RESUMO

Moderate to severe pulmonary hypertension, mean pulmonary arterial pressure (mPAP) > 35 mmHg, in cirrhotic patients is usually considered an absolute contraindication to orthotopic liver transplantation (OLT) because of unacceptably high mortality. We present the case of successful OLT in a cirrhotic patient with a mPAP of 42 mmHg and a pulmonary vascular resistance (PVR) of 298 dyne . sec . cm(-5) preoperatively. He was treated with oral sildenafil (Viagra(R)) and inhaled iloprost (Ventavis(R)) for 45 days and then his mPAP and PVR were reduced to 33 mmHg and 206 dyne . sec . cm(-5) at the time of transplantation. During OLT, his mPAP was stable of 28?38 mmHg with the combined use of sildenafil via a nasogastric tube and iloprost via a nebulizer. His hemodynamic parameters were stable and significant postoperative bleeding was not noticed throughout his stay in the intensive care unit. Thereafter, he was transferred to general ward without any cardio-respiratory problems on 7th postoperative days.


Assuntos
Humanos , Pressão Arterial , Hemodinâmica , Hemorragia , Hipertensão , Hipertensão Pulmonar , Iloprosta , Unidades de Terapia Intensiva , Fígado , Transplante de Fígado , Nebulizadores e Vaporizadores , Quartos de Pacientes , Piperazinas , Purinas , Sulfonas , Transplantes , Resistência Vascular , Citrato de Sildenafila
10.
Korean Journal of Anesthesiology ; : 547-553, 2007.
Artigo em Coreano | WPRIM | ID: wpr-193250

RESUMO

Renal failure frequently accompanies advanced hepatic failure. Even if adequate renal function is not considered as a prerequisite for transplant candidacy, impaired renal function prior to liver transplantation has been regarded as an independent risk factor of graft dysfunction and mortality. Liver transplantation in such a patient also presents a number of challenges to the anesthesiologists. Optimal fluid therapy, prompt and aggressive correction of electrolytes and metabolic disturbances, careful selection of anesthetic techniques and agents, and close monitoring of cardio-respiratory function help reduce the graft failure and perioperative mortality. In such cases, continuous renal replacement therapy (CRRT) is used with increasing frequency during or after the surgery. So, anesthesiologists need to understand the basic principles, potential applications, and anesthetic implications of several CRRT options. We therefore present the anesthetic experience in a patient with hepatic failure combined with primary renal failure, successfully managed during or after liver transplantation.


Assuntos
Humanos , Anestesia , Eletrólitos , Hidratação , Falência Hepática , Transplante de Fígado , Fígado , Mortalidade , Insuficiência Renal , Terapia de Substituição Renal , Fatores de Risco , Transplantes
11.
Anesthesia and Pain Medicine ; : 91-97, 2007.
Artigo em Coreano | WPRIM | ID: wpr-121725

RESUMO

BACKGROUND: Levobupivacaine appears attractive as epidural analgesia because it is less cardio- and neurotoxic than its racemic mixture. This study evaluated the efficacy and safety of two different concentrations of levobupivacaine infused epidurally as analgesia for elderly patients undergoing abdominal surgery. METHODS: This prospective study evaluated the quality of postoperative analgesia, the six graded physical activity score, the time to the first passage of flatus, the time to the first oral intake of clear fluid, and the postoperative hospital stay in patients who received a continuous thoracic epidural infusion of levobupivacaine at two different concentrations over a 48 hour period: Group 0.2% (n = 15) or Group 0.25% (n = 15). The incidence of side effects, such as motor block, hypotension, and bradycardia, was also assessed. RESULTS: There were no differences with regard to the verbal numerical rating scale at rest and cough, the total consumption of rescue analgesia, the incidence of side effects, and the overall satisfaction. The physical activity scores at postoperative 24 and 48 hours were similar in both groups. However, the time to the first passage of flatus and time to the first oral intake of clear fluid was significantly faster in Group 0.25% than in Group 0.2% (P < 0.05). CONCLUSIONS: The continuous thoracic epidural infusion of levobupivacaine in elderly patients after abdominal surgery at both 0.2% and 0.25% provides a similar quality of analgesia without any significant motor block. However, increasing the concentration to 0.25% provides a more rapid return of the bowel function but does not shorten the postoperative hospital stay.


Assuntos
Idoso , Humanos , Analgesia , Analgesia Epidural , Bradicardia , Tosse , Flatulência , Hipotensão , Incidência , Tempo de Internação , Atividade Motora , Estudos Prospectivos
12.
Korean Journal of Anesthesiology ; : 230-232, 2006.
Artigo em Coreano | WPRIM | ID: wpr-119951

RESUMO

We present a case of an anesthetic gas leak through the valve of the Selectatec back bar during a surgical procedure. The Selectatec Vaporizing System is a quick-change system consisting of anesthetic vaporizers of the 'Tec models' of the Ohmeda machine that are seated on a compatibility manifold block located on the back bar of the anesthetic machine. In order to prevent a leak and a failure of vapor delivery, the "Tec models series" can only be turned 'on' when the locking lever is turned to the 'lock' position. However in this case, the control knob was rotated despite the back bar locking mechanism not being engaged, and a gas leak developed through the unlocked valves in Selectatec back bar. The Penlon Sigma Delta Anesthetic Vaporizer (sevoflurane) in a Datex-Ohmeda Aestiva/5 anesthesia machine can be turned 'on' when the locking lever is maintained at the 'unlock' position.


Assuntos
Anestesia , Nebulizadores e Vaporizadores
13.
Korean Journal of Anesthesiology ; : 157-161, 2005.
Artigo em Coreano | WPRIM | ID: wpr-221259

RESUMO

BACKGROUND: Ropivacaine is a long acting, amide-type local anesthetic with a chemical structure similar to that of bupivacaine. In this study we investigated the efficacies of 18 ml of 0.5% bupivacaine, and of 0.5% and 0.75% ropivacaine to provide caudal anesthesia. METHODS: Sixty ASA physical status 1 or 2 patients undergoing hemorrhoidectomy were randomly allocated to 3 parallel treatment groups to receive either 18 ml of 0.5% bupivacaine, or 0.5% or 0.75% ropivacaine. Caudal anesthesia was performed using the loss of resistance method via sacral hiatus. Soft touch testing around the anal sphincter muscle, the pin prick method at the S3 dermatome, onset time of loss of anal sphincter reflex, and sensory block were checked following local anesthetic injection. Duration of sensory block was assessed at 30 minute intervals through out block duration. Quality of muscle relaxation was assessed by the surgeon at the end of each operation. Blood pressures were measured and the incidences of nausea, vomiting and dizziness were recorded. RESULTS: Significant differences were observed between the 0.5% ropivacaine and 0.75% ropivacaine groups (P <0.05) with regard to onset time of loss of anal sphincter muscle reflex and sensory block. The 0.75% ropivacaine group showed a longer duration of analgesia. No significant differences were found between the 0.5% bupivacaine, or the 0.5% or 0.75% ropivacaine groups in terms of the onset time of loss of anal sphincter muscle reflex or sensory block, or the duration of analgesia. Quality of muscle relaxation was similar in the three groups. CONCLUSION: In our study the 0.75% ropivacaine group showed rapid loss of anal sphincter tone, rapid onset of sensory block, and longer analgesia duration than the 0.5% ropivacaine group, and 0.75% ropivacaine was similar to 0.5% bupivacaine in these respects. These results suggest that 0.5% or 0.75% ropivacaine may be as useful as 0.5% bupivacaine in caudal anesthesia for hemorrhoidectomy.


Assuntos
Humanos , Canal Anal , Analgesia , Anestesia Caudal , Bupivacaína , Tontura , Hemorroidectomia , Incidência , Relaxamento Muscular , Náusea , Reflexo , Vômito
14.
Korean Journal of Anesthesiology ; : 565-569, 2005.
Artigo em Coreano | WPRIM | ID: wpr-15792

RESUMO

BACKGROUND: Diabetes mellitus is the most common endocrinopathy encountered in the perioperative period and has long been assumed to increase perioperative risk. However, when diabetes mellitus was segregated from old age and the complications of it, it was questioned that diabetes mellitus itself increased perioperative risk. In this study, we investigated the influence of hyperglycemia on the length of postoperative hospital stay. METHODS: We studied 100 patients undergone intra-abdominal operations with general anesthesia. These patients were divided into the hyperglycemic group (n = 20) with postoperative blood glucose level higher than 10 mM and the non-hyperglycemic group (n = 80) with glucose level lower than 10 mM and we investigated the length of postoperative hospital stay, serum electrolyte, serum chemistry, arterial blood gas values, and base excess by unmeasured anions. We also divided these patients into the diabetic patients group (n = 15) and the non-diabetic patients group (n = 85) and compared the same variables. RESULTS: The length of postoperative hospital stay was significantly prolonged in the hyperglycemic group (20.9 +/- 9.0 days) compared with the non-hyperglycemic group (16.2 +/-8.5 days), and the cumulative postoperative hospital stay curves based on Kaplan-Meier method also showed significant difference between the two groups. When we compared the length of postoperative hospital stay between the diabetic and the non-diabetic patients, there was no significant difference. CONCLUSIONS: This study demonstrated that hyperglycemia prolonged the length of postoperative hospital stay. This finding suggests that the patient's glucose level should be monitored and controlled within an adequate range perioperatively.


Assuntos
Humanos , Anestesia Geral , Ânions , Glicemia , Química , Diabetes Mellitus , Glucose , Hiperglicemia , Tempo de Internação , Período Perioperatório
15.
Korean Journal of Anesthesiology ; : 341-346, 2004.
Artigo em Coreano | WPRIM | ID: wpr-47354

RESUMO

BACKGROUND: Music is widely used to help a patient relax, and divert their attention from unpleasant and stressful situations. In addition, it eliminates the noise in the operating room. A light level of general anesthesia for a cesarean section is usually applied to the mother to improve the fetal safety. Therefore, there is an increased incidence of maternal explicit and implicit memory with the bispectral index (BIS) monitoring. METHODS: Fifty patients undergoing a cesarean section under general anesthesia were allocated randomly to either a control group (group 1) or a music group (group 2). Patients in group 2 listened to music with a headphone during the procedure. The blood pressure, heart rate, intraoperative awareness, postoperative explicit and implicit memory and the plasma cortisol level were assessed. RESULTS: The systolic blood pressure and heart rate were significantly lower in group 2 than group 1 at 1 minute before intubation and 5 minutes after extubation (P <0.05). The BIS value were significantly lower in group 2 than group 1 at 1 minute after intubation and 10 minutes after delivery (P <0.05). The hit ratios of the implicit of memorial test were significantly higher in the group 2 (2.4 +/- 0.7) than in group 1 (1.6 +/- 0.4) (P <0.05). The hits of the implicit memorial test had no corresponding BIS value (P <0.05). The plasma cortisol level was significantly higher group 1 than in group 2 at 30 minutes after intubation and 10 minutes after arriving at the recovery room (P <0.05). CONCLUSIONS: It was found that the music played to the mother during a cesarean section under general anesthesia decreased the anxiety and stress response, and this technique may help protect patients from unwanted explicit and implicit memory.


Assuntos
Feminino , Humanos , Gravidez , Anestesia Geral , Ansiedade , Pressão Sanguínea , Cesárea , Frequência Cardíaca , Hidrocortisona , Incidência , Consciência no Peroperatório , Intubação , Memória , Mães , Música , Ruído , Salas Cirúrgicas , Plasma , Sala de Recuperação
16.
Korean Journal of Anesthesiology ; : 229-237, 2001.
Artigo em Coreano | WPRIM | ID: wpr-72433

RESUMO

BACKGROUND: It is well established that vascular contraction is caused by not only an increase in cytosolic Ca2+ level but also activations of Ca2+-sensitizing mechanisms including protein kinase C (PKC) and low molecular GTP binding protein. However, the roles of PKC and RhoA, a low molecular GTP-binding protein, on the receptor agonist-mediated contraction in swine pulmonary artery has not been clarified. In the present study, we examined the contribution of PKC isoform and RhoA to the arterial stimulants-induced contraction in swine pulmonary artery. METHOD: The large (> 5 mm), medium (1-3 mm) and small (< 1 mm in outer diameter) sized pulmonary arteries were excised and the contractions were recorded isometrically. The contents and subcellular distribution of PKC isoforms and RhoA were detected using immunoblotting. RESULTS: In medium pulmonary artery, norepinephrine (NE, 10 nM-30micrometer) led contraction in a dose-dependent manner. In large and small pulmonary arteries, however, NE failed to induce a contraction. Adding of 12-deoxyphorbol 13-isobutyrate (DPB, 1micrometer), a PKC activator, developed muscle force in 1 mM EGTA-contained Ca2+-free physiological salt solution. The expressions of PKC alpha, elsilon were significantly increased in medium pulmonary artery. NE (10micrometer) evoked the translocation of RhoA from cytosol to the membrane but not those of PKC isoforms. In Ca2+-free physiological salt solution, DPB (1micrometer) caused a translocation of PKC isoforms. CONCLUSIONS: These results support that NE induces contraction via RhoA pathway but not PKC pathway in swine pulmonary artery.


Assuntos
Citosol , GTP Fosfo-Hidrolases , Proteínas de Ligação ao GTP , Immunoblotting , Membranas , Norepinefrina , Isoformas de Proteínas , Proteína Quinase C , Proteínas Quinases , Artéria Pulmonar , Suínos
17.
Korean Journal of Anesthesiology ; : 933-938, 1998.
Artigo em Coreano | WPRIM | ID: wpr-192192

RESUMO

Background: Post-dural puncture headache (PDPH) is one of the well-known complication of spinal anesthesia. Epidural blood patch is the treatment of choice for PDPH but is rarely used for the prevention of PDPH after spinal anesthesia. The purpose of this study is to observe the effectiveness of epidural blood patch for prevention of PDPH and to evaluate the complications after epidural blood injection. Methods: Three hundred patients (ASA I or II) receiving spinal anesthesia were studied. They were randomly devided into two groups. Patients in Group I, the control group, were maintained in a supine position for 24 hour after spinal anesthesia. Patients in Group II, the study group, received 3 ml of autologous blood in the epidural space after spinal anesthesia. PDPH was evaluated for 5 days. The incidence, location, onset, and duration of headache in the patients presenting with PDPH were measured for 5 days, and the complications following epidural blood patch in Group II were observed for 2 weeks. Results: The incidence of PDPH in group I was 11%, but 0% in group II. There were no specific complications following epidural blood patch in Group II. Conclusions: This study suggest that the 3 ml epidural autologous blood patch is an useful method for the prevention of PDPH in patients with spinal anesthesia.


Assuntos
Humanos , Raquianestesia , Placa de Sangue Epidural , Espaço Epidural , Cefaleia , Incidência , Cefaleia Pós-Punção Dural , Punções , Decúbito Dorsal
18.
Korean Journal of Anesthesiology ; : 463-466, 1998.
Artigo em Coreano | WPRIM | ID: wpr-90471

RESUMO

BACKGROUND: Myasthenia gravis is an autoimmune neuromuscular disorder that shows increased sensitivity to nondepolarizing muscle relaxants. Atracurium is eliminated by Hofmann elimination and ester hydrolysis. We studied the onset and duration of atracurium in patients with myasthenia gravis. METHODS: Ten patients undergoing thymectomy for myasthenia gravis and ten patients of ASA Class I-II without liver, kidney and neuromuscular disease for orthopedic surgical procedures were assigned. Anesthesia was induced with thiopental (4~5 mg/kg) and maintained with inhalation of N2O:O2 (1:1) and enflurane (1.0~2.0 vol%). Atracurium (0.5 mg/kg) was given as a muscle relaxant and then intubation was performed after twitch response was depressed more than 80%. Neuromuscular relaxation was assessed by TOF (T1) at the adductor pollicis with supramaximal stimulation of ulnar nerve at 2 Hz every 12 seconds. The onset and the duration of 5, 25, 50, 75% recovery time of T1 and the recovery index were recorded. RESULTS: Onset of block was shortened and recovery time of 5, 25, 50, 75% and recovery index were prolonged in patients with myasthenia gravis. Conlusions: In patients with myasthenia gravis, atracurium induced rapid onset time and prolonged recovery time of 5, 25, 50, 75% and recovery index.


Assuntos
Humanos , Anestesia , Atracúrio , Enflurano , Hidrólise , Inalação , Intubação , Rim , Fígado , Miastenia Gravis , Doenças Neuromusculares , Procedimentos Ortopédicos , Relaxamento , Tiopental , Timectomia , Nervo Ulnar
19.
Korean Journal of Anesthesiology ; : 720-725, 1996.
Artigo em Coreano | WPRIM | ID: wpr-72620

RESUMO

BACKGROUND: Most surgical patients experience preoperative anxiety. This anxiety can effect the amount of preanesthetic medication and anesthetic agents needed, and contribute to postoperative pain. Music has been recognized as a way to reduce anxiety and fear. The effect of hymn and sutra-chanting on the preanesthetic patient's anxiety in the operating room were studied. METHODS: 98 patients were divided into two groups according to the religionist or atheism. Group I(n=50, religionist) and Group II(n=48, atheism) listened to hymn or sutra-chanting according to the patient's religion and choice. At ward, hemodynamic variables including systolic and diastolic blood pressure and pulse rate were measured as control values. Hemodynamic variables and measurements of anxiety score with Hamilton anxiety rating scale were made at pre-music and post-music in the operating room. Also, patient's response to the music was measured on the postoperative 5-6th day. RESULTS: There were no difference between ward, pre-music, and post-music in terms of systolic pressure, diastolic pressure and pulse rate except the systolic pressure at pre-music that is grater than that of controls in both groups. Both group, anxiety score at post-music was significantly lower than that of pre-music (10.2+/-3.4 vs 4.4+/-2.9, 11.0+/-3.2 vs 5.7+/-3.1). At post-music, anxiety score in Group I showed significant reduced compaired with Group II (p<0.05). Patients showed relatively good satisfaction with music in both groups. CONCLUSION: The results suggest that music with hymn and Sutra-chanting were effective to reduce preanesthetic anxiety in both religionist group and atheism group.


Assuntos
Humanos , Anestesia , Anestésicos , Ansiedade , Pressão Sanguínea , Frequência Cardíaca , Hemodinâmica , Música , Salas Cirúrgicas , Dor Pós-Operatória , Medicação Pré-Anestésica , Pré-Medicação
20.
Korean Journal of Anesthesiology ; : 590-593, 1995.
Artigo em Coreano | WPRIM | ID: wpr-155159

RESUMO

The continuous epidural anesthesia is an effective method for postoperative pain control and improvement of pulmonary function. A 39-year-old man was scheduled for postoperative intestinal obstruction. After adhesiolysis under the general anesthesia, epidural anesthesia was done for postoperative pain control. Because an accidental dural puncture was noticed, the adjacent interspace of epidural anesthesia was tried and catheter was inserted. Respiratory depression, hypotension, loss of consciousness and cardiac arrest were developed about 20 minutes after the first injection of 1% lidocain 10ml. Endotracheal intubation was performed and the respiration was controlled using 100% oxygen. Self respiration and alert mentality returned after 180 minutes. No CSF leakage, delayed onset time, severe hypotension, complete recovery may be the result of subdural anesthesia and postoperative hypoxia. But radiological examination was not performed.


Assuntos
Adulto , Humanos , Anestesia , Anestesia Epidural , Anestesia Geral , Hipóxia , Catéteres , Parada Cardíaca , Hipotensão , Obstrução Intestinal , Intubação Intratraqueal , Oxigênio , Dor Pós-Operatória , Punções , Respiração , Insuficiência Respiratória , Inconsciência
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