1.
Indian J Exp Biol
;
1980 Jan; 18(1): 6-8
Artigo
em Inglês
| IMSEAR
| ID: sea-55620
2.
Indian J Physiol Pharmacol
;
1979 Apr-Jun; 23(2): 115-20
Artigo
em Inglês
| IMSEAR
| ID: sea-107457
RESUMO
Toxicological study was carried out in rats with chloroform-soluble fraction of the nuts of Semecarpus anacardium to determine its safe non-toxic dose. The fraction produced toxicity at all levels tested (50-400 mg/kg) but the extent of toxicity was found dose-dependent. At lower doses this fraction induced partial growth inhibition over 36 days and higher doses proved fatal within 6 days. It was observed that 230 mg/kg caused 50% mortality in rats and this value is 1380 mg/m2 when expressed for body surface area. This work will be of some use in the cancer chemotherapy study of the fraction.
Assuntos
Animais , Comportamento Animal/efeitos dos fármacos , Peso Corporal/efeitos dos fármacos , Dose Letal Mediana , Masculino , Nozes , Extratos Vegetais/toxicidade , Plantas Medicinais , Ratos , Fatores de Tempo
3.
Indian J Cancer
;
1977 Dec; 14(4): 320-4
Artigo
em Inglês
| IMSEAR
| ID: sea-50934
Assuntos
Adolescente , Adulto , Antineoplásicos/uso terapêutico , Criança , Cobre/sangue , Quimioterapia Combinada , Feminino , Doença de Hodgkin/sangue , Humanos , Masculino
4.
Indian J Cancer
;
1977 Dec; 14(4): 313-6
Artigo
em Inglês
| IMSEAR
| ID: sea-50560