Sustainable Rates of Sebum Excretion in Relation to Menstrual Cycle / 대한피부과학회지

Sustainable rates of sebum excretion(SRSE) was measured in seven women who had normal regular periods, none were taking oral contraceptives with no significant signs of acne or hirsutism, with assays for testosterone, dihydrotestosterone, dehydroepiandrosterone sulfate, and progesterone during menstrual cycle. The SRSE in omen during the follicular phase wa lower in the luteal phase (p <0.01)than in the men (p <0.01). However during the luteal phase the SRSE in the women was increased similar to the SESE in the men. We investigated the above horrnoies in relationship to the SRSE during the women's menstrua] cycle. During the follicular phase the hormone which was the most determining factor affected the SRSl was total testerone, while dihydrotestosterone was the most determining factor of the horrnone affecting the SRSE during the ovulation and luteal phase.

A Study for The Effects of UV exposure and UV Exposure After Being Applied by Sunscreens on Hepatic Microsomal Cytochrome Enzyme System and Vitamin D in Newborn Rats / 대한피부과학회지

We observe changes of activation of hepatic microsomal cytochrome p-450, changes of formation of riug-and N-hydroxylation of 2-acetylaminofluorene, and changes of vitamin D, in the liver which exposed to UV light and expoeed to UV light after being applied by sunscreens. The results of our study are as shown below: 1. The contents of hepatic microsomal cytochrome p-45p of newborn rats were found to be remarkably increase in the group exposed to UV light for 3 weeks (p<0. 001), but such changes were much reduced in the group exposed to UV light for 3 weeks after being applied by sunscreens(p<0.05. p<0.001, ) 2.Cytochrome p-450 induced by UV light was found to be significantly increased ring and N-hydroxylation of 2-acetylarninofluorene known as carcinogenic source for the liver. In the group exposed to UV light for 3 weeks after being applied by sunscreens, both of ring-and N-hydroxylation of 2-acetylaminofluorene were significantly reduced(p<0. 0, p<0. 001). 3, The contents of vitarnin D, in the liver of newborn rats were found to be gradually increased when they were exposed to UV light for 1 week or 3 weeks (p<0. 001), and in the group exposed to UV light after being applied by sunscreens, such changes were reduced remarkably(pg0. (301).

A Case of Allergic Vasculitis Associated with Chronic Active Hepatitis / 대한피부과학회지

Hepatitis B virus is of growing clinical importance. This virus not only produces acute and chronic liver disease but also produces a variety of dermatologic syndromes. A 77-year-old man with erythematous urticarial-like papulonodules had a chronic active hepatitis. And microscopic findings were compatible with allergic vasculitis. We reported a case of allergic vasculitis associated with chronic active hepatitis and reviewed literatures briefly.

A Case of Atypical Linear Porokeraotsis / 대한피부과학회지

Porokeratosis is a familial, chronic, progressive disorder which demonstrates a characteristic clinical and histologic picture. Since Mibelli described three cases in 1893, several clinical variants have been identified, all of which are delineated by a diagnostic histopathologic pattern. We reported a case of atypical linear porokeratosis that had three types of skin lesions. One was the plaque type, as originally described by Mibelli. And others were atypical lesions, as papules and verrucoid hyperkeratotic plaques.

A Case of Hypertrophic Lichen Planus / 대한피부과학회지

A 17-year-old high School boy showed multiple, various sized, grayish or violaceous scaly verrucous plaques on the entire body including the oral mucosa, both soles and palms. We considered this is the first case that involves entire body including the oral mucosa, both soles and palms in dermatologic literatures. We reported this case and reviewed briefly literature