Influence of vanadium on lipid profiles and lipid peroxidation in rat liver

Twenty four adult male Sprague-Dawley rats were administered sodium matavanadate [2.5 mg/kg body wt] for 7 consecutive days by intraperitoneal route. Results revealed significant diminution in the levels of phospholipids, cholesterol and cerebrosides, but significant increment in gangliosides contents in rat liver following vanadium-treatment. Occurrence of lipid peroxidation was also accelerated. These studies have implicated that vanadium-induced stimulation of lipid peroxidation was the event leading to oxidative degradation of lipids in rat liver. However, malfunctioning of gangliosides led to their increment

Lipoprotein-bound cholesterol levels in Libyans

The level of cholesterol and its distribution among different serum lipoproteins of a homogenous local Libyan population at Benghazi is reported. The level of total cholesterol appears to be low in the population in general and appears to fit the suggested ideal value. Females had lower levels of serum total cholesterol than males and there was a marked increase in cholesterol with age. Physical activity does not appear to significantly alter cholesterol level in the population. The genetic makeup of a race may also seem to play a vital role in determining the cholesterol level

Glucose-6-phosphate dehydrogenase deficiency in Libya: an appraisal of gene frequency in Arabic regions of Africa and West Asia

Screening of glucose-6-phosephate dehydrogenase [G6PD] deficiency in erythrocytes of 400 healthy Libyan males revealed an incidence of 2.5% in a random Benghzia population. The quantitative levels among enzyme-deficient individuals ranged from 0 to 20% of the normal activity. Distribution of Gd gene in North Africa and Arabian peninsula is discussed in the light of malarial endemicity