Sodium methoxide: a single remarkable UV shift reagent in structure analysis of flavonoids. Part I: flavones and 3-o-substituted flavonols

Sodium methoxide was applied in studying various oxygenation patterns of flavonoids. The Na OMe spectra of different groups of flavones displayed definite and characteristic absorption profiles, which explicitly reflected specific hydroxylation patterns. Examination of the MeOH and NaOMe spectral data granted the potential use of this reagent to determine the possible oxygenation pattern on the flavonoid nucleus

Coumarins with antiviral and cytotoxic activity from Egyptian panunculus asiaticus L

Three coumarins were isolated from the CHCl3 extract of the aerial parts of Ranunculus asiaticus L. [Ranunculaceae]. They were identified as aesculetin dimethyl ether [6,7-dimethoxy-coumarin] [I], isoscopoietin [II] and scopoietin [III], based on their spectral and physical data. The cytotoxic and antiviral activities of I and III were evaluated

Flavonoids from carduus pycnocephalus l

Two flavonoids were isolated from the ether extract of the aerial parts of C. pycnocephalus L. [Asteraceae]. They were identified as diosmetin [I] and kempferol-3-O-alpha-L-rhamnoside [II] by different spectroscopic techniques, in addition to acid hydrolysis of II, and comparison of the sugar with reference samples. Three known sterols were also isolated

effect of substituted pattern on the Rf value of flavones

The effect of substitution pattern on the polarity of flavonoid aglycones and the relation between the Rf value and structure of these compounds have been assessed

13C-NMR assessment and Antimicrobial activity of desacetylnemorone; a major diterpenequinone from salvia lanigera poir

The structure of desacetylnemorone, a major diterpenequinone, previously isolated from Salvia lanigera Poir., was confirmed by 13C-NMR, DEPT 135 and DEPT 90. In addition, this compound was evaluated for antimicrobial activity

Diterpene quinones from the roots of salvia lanigera poir

Fractionation of the antimicrobial petr. extract of Salvia lanigera Poir. roots, afforded two more diterpene quinones deoxyneocryptotanshinone I and 7-oxoroyleanone II. Their structures were elucidated using 400 MHz 1H-NMR and other spectroscopic evidences

Failure of intramedullary nails

The incidence of broken I.M.N. is increasing, so that a detailed study of this problem must be made, to discus the responsible factors leading to it. Forty patients with broken I.M.N. were reviewed and evaluated to discover the contributing factors. It was proved that there are many factors responsible: As with bad technique, improper nail and the state of healing at the fracture site. All these factors and others were discussed in this study

Diterpenoidsin the genus salvia 1-diterpene quinones

The increasing number of structurally interesting and biologically active diterpene quinones that have been discovered and still to be isolated from many members of the genus salvia calls for an update review. This article desribes the recent advances in their structural variation and distribution pattern in the different studied species