Evaluation of the immune response against Pasteurella multocida

The control of pasteurellosis caused by Pasteurella multocida in rabbits remains a problem despite the vaccine available for influence subsequent rabbit reproduction performance and extent the immunity throughout the largest period. Different inactivated vaccines against pasteurellosis [Heat, Formalinized, Binary ethyleneimine [BEI] irradiated and potassium thiocyanate [KSCN] were prepared. These vaccines were tested by indirect haemagglutination test [IHT] to measure the average titers of antibodies in experimental rabbits. Data revealed that, among the tested inactivated vaccines, irradiated and KSCN gave the highest values of the overall mean of antibodies, as post-vaccination, being 1236.8 as compared to the other inactivated vaccines, followed by BEI and formalized inactivated vaccines [946.5 and 856.8, respectively when tested at 7,15,21,35,45 and 60 days. However, heat inactivated vaccine gave the lowest value, being 688.2 when estimated at the same time. Using bioassay test in rabbits, results revealed that KSCN vaccine gave the highest value, being 100% of protection against virulent strain of Pasteurella multocida. These results were followed by BEI and heat vaccine, being 90% protection, while formalinized vaccine and irradiated vaccine gave 80% protection. It was concluded that potassium thiocyanate extract vaccine is the best vaccine for protection against pasteurellosis in rabbits

Clinical failure of ceftriaxone treatment in a patient with penicillin resistant pneumococcal meningitis.

A case of meningitis caused by penicillin resistant Strep.pneumoniae is described for the first time in our hospital. This case also showed treatment failure with Ceftriaxone. Patient was successfully treated with Imipenem. It is recommended that routine screening for penicillin resistance in meningeal isolates be done and in such instances, the MIC levels for third generation cephalo-sporins also be performed to detect resistance of any type

Group D salmonella as cause of urinary tract infection

A case of primary urinary tract infection caused by group-d salmonella is presented. Even though it is not the usual pathogen at this site, it proves that under certain circumstances this enteric pathogen can cause urinary tract infection. Other reported cases are also reviewed

search for histoplasma capsulatum in bats from Sakara area near Cairo

From the caves inhabited by bats in Sakkara region, 100 bats were collected for studying whether these bats are carrier for H. Capsulatum or not. All the examined cultures from the bats' internal organs were negative for H. Capsulatum. This study suggests the rarity of histoplasmosis in this area