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1.
Indian Pediatr ; 2011 December; 48(12): 967-968
Artigo em Inglês | IMSEAR | ID: sea-169042
2.
Indian J Dermatol Venereol Leprol ; 2007 Jul-Aug; 73(4): 280
Artigo em Inglês | IMSEAR | ID: sea-52050

RESUMO

A sixteen year-old male patient with no history of consanguinity in the family, reported with patchy, thickened lichenified plaques over the whole body. Some areas had normal skin while some were Blaschkoid lesions. The child had delayed milestones along with hypogonadism. Digital contracture with palmoplantar keratoderma was present. Histopathology showed characteristic vacuolar degeneration of the upper epidermis and suprabasilar keratinocytes with hyperkeratosis.


Assuntos
Adolescente , Contratura/etiologia , Dedos/patologia , Humanos , Hiperceratose Epidermolítica/classificação , Hipogonadismo/etiologia , Ceratodermia Palmar e Plantar/patologia , Masculino , Mosaicismo , Pele/patologia
3.
J Indian Med Assoc ; 2007 Mar; 105(3): 141, 148
Artigo em Inglês | IMSEAR | ID: sea-96613

RESUMO

Systemic lupus erythematosus is a multisystem organ inflammation due to damage of cells and tissues by pathogenic auto-antibodies and immune complexes. The most important factor for the causation of familial systemic lupus erythematosus is genetic on which environmental factor usually coexists. Two brothers of 7 and 3 years of age having childhood systemic lupus erythematosus are reported here because of low incidence and familial occurrence. Both the children fulfilled the American Rheumatology Association (ARA) criterion of systemic lupus erythematosus though anti-dsDNA was negative in both and antinuclear factor was positive only in the younger child. Systemic lupus erythematosus begins in childhood in 20% of adult patients and usually after the age of 8 years but here onset was even at an earlier age. The treatment of the both the siblings included administration of steroids and cyclophosphamide.


Assuntos
Criança , Pré-Escolar , Ciclofosfamida/administração & dosagem , Esquema de Medicação , Humanos , Imunossupressores/administração & dosagem , Lúpus Eritematoso Sistêmico/diagnóstico , Masculino , Prednisolona/administração & dosagem , Irmãos
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