1.
Japanese Journal of Complementary and Alternative Medicine
;
: 35-38, 2009.
Artigo
em Japonês
| WPRIM
| ID: wpr-376470
RESUMO
<i>Objective</i>: Angiotensin I Converting Enzyme was used to study the inhibitory activity of porcine placenta extracts.<br> <i>Methods</i>: ACE was derived from rabbit lung. Bz-Gly-His-Leu was used as a substrate. Production of hippuric acid was measured by HPLC.<br> <i>Result</i>: ACE inhibitory activity was measured in a two-fold dilution of porcine placenta extracts. The IC<sub>50</sub> of porcine placenta extracts was 95.7 μg. The results of a Lineweaver-Burk plot suggested that porcine placenta extracts exhibited a competitive inhibition.<br> <i>Conclusion</i>: In this paper, we found that porcine placenta extracts had an anti-ACE activity.<br>