1.
Indian J Lepr
;
2000 Jul-Sep; 72(3): 339-50
Artigo
em Inglês
| IMSEAR
| ID: sea-54262
2.
Indian J Lepr
;
1999 Jan-Mar; 71(1): 69-74
Artigo
em Inglês
| IMSEAR
| ID: sea-54626
3.
Indian J Lepr
;
1996 Jan-Mar; 68(1): 67-73
Artigo
em Inglês
| IMSEAR
| ID: sea-54265
4.
Indian J Lepr
;
1995 Oct-Dec; 67(4): 363-74
Artigo
em Inglês
| IMSEAR
| ID: sea-54232
RESUMO
Various mechanisms for nerve damage in tuberculoid leprosy have been proposed. A common feature amongst them is the crucial role played by T-cells. Therefore, the present study was designed to determine the role of T-cells in the induction of nerve damage in leprosy using two different protocols for obtaining graded levels of T-cell depletion: (i) Cyclosporine A, for depletion of T-helper cells and (ii) Anti Thy 1.2, for total depletion of T-cells. The findings indicate that the early changes seen in the unmyelinated fibres may not involve T-cells. However, the later stages of nerve damage associated with demyelination are dependent on T-cell responses.
Assuntos
Animais , Ciclosporina/farmacologia , Doenças Desmielinizantes/etiologia , Feminino , Isoanticorpos/imunologia , Hanseníase/microbiologia , Camundongos , Mycobacterium leprae/crescimento & desenvolvimento , Nervo Isquiático/patologia , Linfócitos T/fisiologia
5.
Artigo
em Inglês
| IMSEAR
| ID: sea-118994
6.
Indian J Lepr
;
1991 Jul-Dec; 63(3-4): 297-300
Artigo
em Inglês
| IMSEAR
| ID: sea-54538