[Secondary plasma cell leukemia about of 2 cases]

Plasma cell leukemia is considered as the leukemic variant of multiple myeloma. It is a rare entity. There are two forms: a secondary one following a known myeloma, the diagnosis of which is easy, and a primary one arising without a preceding phase of multiple myeloma. The diagnosis of the latter form is more difficult, a differential diagnosis has often to be discussed with other lymphoproliferative diseases. Prognosis is poor. We report 2 cases of secondary plasma cell leukaemia diagnosed over ten years, among 59 of multiple myeloma cases. We describe the epidemiologic, clinical, biological and evolutionary characteristics

Aspects diagnostique et therapeutique de la tuberculose ganglionnaire: a propos de 42 cas

We report a retrospective study of 42 cases of lymphnode tuberculosis. We noted symptoms of tuberculosis impregnation in 92%, cervical localization in 71%, positive tuberculin intra- dermo-reaction in 77%, and accelerated erythrocyte sedimentation rate in 73% of the cases. Koch bacillus was detected in expectoration, urine or gastric liquid at the rate of 11% of the cases. Lymph node puction was suggestive in 4 out of 12 patients, showing giant cells with or without caseum. Lympth node biopsy, performed in 32 patients, was contributive in 94% of them. Another tuberculous localization was found in 14 cases mainly pulmonary [8 cases]

Les manifestations cliniques et biologiques des leucemies aigues lymphoblastiques de l'enfant [etude retrospective de 87 cas]

We present in this study the clinical and biological datas of 87 children suffering from acute lymphoblastic leukemia followed between 1985 and 1996. The mean age was 7 years; 37% of the patients were aged under 5 years at diagnosis. The sex ratio was 1.35. the anemic, infection and hemorrhagic syndromes were observed in respectively 65%, 18% and 11% of the patients. Adenopathies were found in 70% splenomegaly and/ or hepatomegaly in 75% Hyperleucocytosis was found in 64%, anemia in 90% and thrombopenia in 85% of the cases. Using the FAB classification we found 72% type 1, 22% type 2 and 6% type 3 acute lymphoblastic leukemia. Cerebro- spinal fluid study revealed meningeal leukemic involvement in 17% of cases