Stage I cancer ovary: Diagnostic modality in our locality

The main objective was to evaluate the diagnostic tools used for diagnosis of stage 1 ovarian cancer. This is a descriptive study was conducted during the period from 1999 to 2003 at Sohag University Hospital. 53 patients out of 212 had stage I ovarian cancer was included in the study. They subjected to thorough history taking, proper examination and routine investigations. Ultrasonography with Doppler flowmetry, CT, IVP and CA-125 were done for all patients. Surgical staging and histopathologidal examination of all specimens was carried out. Ovarian cancer represented the most common type of genital tract malignancy 124[64.92%] 53[25%], 11[5.18%], 114 [53.77%] and 34[16.03%] cases were diagnosed as stage I, II. III and IV respectively, 27 patients [50%] with stage I ovarian cancer were symptoms at time of diagnosis. The most common symptoms in stage 1 ovarian cancer was abdominal swelling or fullness. Both of CT scan and Ultrasonography examination were found to be better than the clinical impression based on symptoms and signs in predicting the malignant nature of ovarian masses

effectiveness of a second course of radiation therapy treatment of recurrent or persistent pain in bone metastases

Twenty-eight patients with recurrent or persistent bone pain after previous radiation therapy for metastatic bone lesions from different primary tumors were retreated by radiation therapy. Patients had received initial palliative radiation course of 30 Gy divided into 10 fractions over two weeks. This study aimed to evaluate the clinical feasibility of retreatment of painful bone metastases. All patients received single radiation dose of 4 Gy. For purpose of data analysis, patients were classified into two groups: The first group included patients with persistent and recurrent pain within three months, while the second group included patients with recurrent pain after three months. Response to retreatment was correlated to pathology of primary tumor, site of bone metastases, number of bone metastases, initial response and time to pain recurrence. The results indicated that patients who achieved initial complete response with recurrent bone pain after nine months and with limited number of bone metastases are more likely to respond to re-irradiation. On the other hand, patients with recurrent bone pain within three months are less likely to benefit from a second course of radiation therapy. Response to re- irradiation was greater in patients with breast carcinoma and with metastases in long bones

Pediatric Hodgkin's disease in upper Egypt

48 children younger than 16 years were diagnosed, staged and treated in Radiotherapy, Pediatric and Surgical Departments [Assiut University Hospital]. During the period from January, 1987 to December 1991 Most of cases were in their first decade [65.4%]. Male predominated representing 72.92% and male to female ratio was 2.69:1. Mixed cellularity occurred, in 52.08%, nodular sclerosing in 14.5%, lymphocytic predominance in 27.08% and lymphocytic depletion in 6.26%. More than one half of the cases [56.24%] were in stage III and IV at presentation. The mediastinum was involved in 4.1%.The treatment strategy was radiotherapy for early cases and chemotherapy for late cases. The treatment responses were excellent in the early cases and had in the late cases. This could be attributed to high tumour burden as well as malnutrition