[Frequency of psychiatric disorder symptoms in diabetic patients of Yasuj City in 2014]

Introduction and Aims: Psychiatric disorders are common to reducing social functioning. Diabetic patients are vulnerable group against this kind of disorders. The aim of present study was investigation of the prevalence of psychological disorders in diabetic patients

Materials and Methods: In this cross-sectional and discriptive study, 100 persons from the statistical population were selected by convenience sampling as experimental group and there were 100 non-diabetic patients in control group. Two groups were matched in age, education and socio-economic status and were assessed by means of SCL-90-R test, containing 90 items for psychiatric disorders evaluation. The cut off point of 0.4 has been reported for Iranian society. To analyze the data, descriptive statistics and the results of SCL-90 were used, at the significant level p<0.01 in SPSS v.21

Results: According to the results the prevalence of psychiatric disorders in diabetic patients were more than non-diabetics. The highest and lowest scores in people with diabetes were due to anxiety and psychosis respectively

Conclusion: Diabetic patients are particularly vulnerable to developing mental health disorders. Regular assessment and timely referral to treatment would increase mental health interventions and appropriate investments to improve the policies. It seems that psychiatric disorders has a considerable role in quality of life of patients with diabetes

Cytokine status in Ukrainian children with irritable bowel syndrome residing in a radioactive contaminated area

The effect of low dose radiation on immune system is shown. Ionizing radiation can affect cytokine production and polarization of T helper cells. The current study focused on ionizing radiation in Ukrainian children residing in a contaminated area with clinical irritable bowel syndrome. Our study included 75 rural children population aged 4-18 yrs, who lived in a contaminated area exposed to natural environmental radiation with clinical irritable bowel syndrome [categorized in three groups] and 20 rural children participants aged 5-15 yrs who were living in areas with similar levels of radioactive contamination without clinical irritable bowel syndrome as control group. Internal radiation activity was measured by gamma-ray spectrometry. Serum levels of IL-4 and IFN-gamma were measured by enzyme linked immunosorbent assay. A trend towards increased levels of IL-4 was observed in children with clinical irritable bowel syndrome. In these children, IFN-gamma levels were lower than that of the control group. The IBS symptoms in Ukrainian children residing in a contaminated area may have stemmed from Th1 to Th2 immune deviation and differential expression of IL-4 and IFN-gamma

Dysbiosis in Ukrainian children with irritable bowel syndrome affected by natural radiation

Microbiota has an important role in human metabolism, nutrition, immunity, and protection against colonization by pathogenic microorganisms. Radiation can harm the beneficial members of the gastrointestinal tract flora. Our study included 75 rural children population aged 4-18, who lived in contaminated area exposed to natural environmental radiation with clinically symptom of irritable bowel syndrome and 20 healthy urban participant aged 5-15 as control group. The intestinal bacterial microbiota was examined from stool samples. Our results indicated the population levels of microbiota such as Enterobacter, Enterococcus, Lactobacillus and Bifidbacterium in caecal contents in 61 subjects [81.3%] was significantly less than in control group. We investigated alternation of the intestinal microbiota affecting by ionizing radiation in children with clinically syndrome of irritable bowel syndrome