Studies on resistance / sensitivity pattern of bacteria related with urinary tract infections

In order to determine the resistance pattern against five different groups of antimicrobial agents, six different species of bacteria were isolated from among two hundred cases of UTIs. The front line antibiotics for treating urinary tract infection due to Escherichia coli, Klebsiella species, Staphylococcus aureus and Proteus species should include Cephradine, Ofloxacin, Cefaclor, Cephalothin and Pipemidic acid. However, for treating UTI due to Pseudomonas species, the drug of choice must be a member of fluoroquinoline group [norfloxacin, ofloxacin and ciprofloxacin]

Post surgical wound infections: a study on threats of emerging resistance

300 bacterial isolates associated with post surgical wound infections were tested in vitro for their sensitivity/resistance pattern against 20 antibacterial agents. The study indicated that the bacteria in which clinically significant resistance has now become a potential problem include Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Proteus. Klebsiella, Staphylococcus epidermidis, Enterobacter and Citrobacter species. Among the tested drugs the percent resistance rate observed were tobramycin [9.75%], amikacin [10.03%], enoxacin [20.53%], ofloxacin [25.93%], ciprofloxacin [26.27%], gentamicin [29.03%], ceftrioxone [36%], aztreonam [41.07%], cefaclor [44.07%]. The conclusion from the study can be drawn that tobramycin and amikacin [aminoglycosides] and enoxacin, ciprofloxacin and ofloxacin [Fluoroquinolones] are very effective agents for treating post surgical wound infections. However resistance to these agents is rapidly increasing