1.
Alexandria Journal of Pharmaceutical Sciences. 1998; 12 (1): 15-20
em Inglês
| IMEMR
| ID: emr-47416
2.
Alexandria Journal of Pharmaceutical Sciences. 1997; 11 (1): 9-12
em Inglês
| IMEMR
| ID: emr-43824
RESUMO
Various substituted and unsubstituted pyridazine-3, 6-diones were prepared in a good yield via the reaction of p-nitrobenzoic acid hydrazide with diacyltartaric acid anhydride, maleic or phthalic acid anhydride [I-IV]. Then, each pyridazinone derivative was condensed with urea, thiourea or hydrazine to afford the corresponding pyridazinotriazine or triazolopyridazine derivatives [V-XVI], respectively. The spectral properties of the products were studied and the antimicrobial activity was evaluated