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Annals Abbassi Shaheed Hospital and Karachi Medical and Dental College. 2002; 7 (2): 387-395
em Inglês | IMEMR | ID: emr-58919

RESUMO

To study the effects of Tamoxifen on long bones, i.e. Femur, Tibia and Humerus of Postmenopausal Aged Female Albino Rats Setting: Basic Medical Sciences Institute [BMSI], Jinnah Postgraduate Medical Centre [JPMC], Karachi Specimens: Ninety bones comprising humerus, femur and tibia [30 each] Methodology: Quantitative measurement of BMC [bone mineral content] and BMD [bone mineral density] carried out by DEXA [Dual Energy X ray Absorptiometry] Scanning Device; Qualitative changes mapped out through plain radiology. Bones, i.e. Femur, Tibia and Humerus of Tamoxifen treated group were found to have relatively increased levels of BMC and BMD. X-rays revealed that bones have greater cortical density in case of tamoxifen treated group. Tamoxifen helps preserving bone mass in bones of Aging Female Albino rats


Assuntos
Animais de Laboratório , Osteoporose Pós-Menopausa/tratamento farmacológico , Ratos , Absorciometria de Fóton , Densidade Óssea
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