RESUMO
Study on the effect hypoglycemosis of extract from Sambucus nigra ssp. canadensis (L) R. Bolli flowers on streptozotocin-induced diabetic mice. A single daily dose of extract (equivalent to 0.4g flower/kg daily) were administered for 5 days or 10 days to the diabetic mice immediately following Streptozotocin injection. As a result, extract from Sambucus nigra ssp. canadensis (L) R. Bolli flowers inhibited glucose concentration in diabetic mice at the investigated dose. It is indicated that the flowers of Sambucus nigra ssp. canadensis (L) R. Bolli may be an effective agent for treatment of diabetes
Assuntos
Hipoglicemia , Medicina Tradicional , Preparações FarmacêuticasRESUMO
In the flowers of Sambicus nigra, flavonoids, amino acids and sugars were determined. Among them the main components were flavonoids, which accounted for 7,19±0,10%. From total flavonoid extracts, ,2 compounds were isolated by column chromatography and identified by UV,MS,and NMR spectroscope as quercetin-3-α rhamnopyranosyl- β -glucopyranose and quercetin