Extraskeletal osteosarcoma developing in metaplastic ossification in a lipoma

A case of extraskeletal osteosarcoma in the thigh of a 45 year old male is reported. The tumour was found to have evoluted from a focus of metaplastic ossification in the lipoma which had existed for about 10 years. There are very limited acceptable reports for the development of extraskeletal osteosarcoma from metaplastic bone in the soft tissues. Possible sequence of events leading to the development of soft tissue osteosarcoma in the present case are suggested

Lipoma of the corpus callosum

A case of Iipoma of the corpus callosum in a 30 years old female is reported. Diagnosis was provisionally made radiologically and confirmed histopathologically. The clinical and pathological features are briefly reviewed

Surgical pathology of thyroid diseases in the Northern part of Iraq

During the years 1978-1983, 1100 thyroid biopsies were received in the pathology department of Mosul Medical College. Analysis of these biopsies showed: 79.1% colloid goitre [diffuse and nodular], 9.1% adenoma, 4.3% toxic goitre, 4.3% malignant neoplasm, 2.3% Hashimoto's thyroiditis, 0.5% de Quervain's thyroiditis, 0.3% parasitic infestation, 0.1% Reidle's thyroiditis, 0.1% tuberculosis, 0.1% pyogenic infection. The age and sex distributions were presented and some of the aetiological factors and preventive measures were reviewed

Carcinoma cells in direct peripheral blood smear [carcinocythaemia]

Nonhaemopoietic malignant cells were identified directly in a routine peripheral blood smear from a patient not known previously to have a neoplasm. The malignancy was later confirmed from a lymph node biopsy. The patient died a week later. Only 7 such cases [Carey et al. 1976, Dannaher et al 1979, Ejeckam et al. 1979, Finkel and Tishkoff 1960, Krause 1979, Myerowitz et al. 1977, Rappaport 1963] have previously been reported in which carcinoma cells were seen in Romanowsky-stained peripheral blood smears without the application of concentration techniques. The presence of highly abnormal cells in the direct peripheral blood smear should arouse suspicion of malignancy originating not only from haemopoietic tissue but also from nonhaemopoietic tissue. The presence of carcinoma cells in a routine blood smear usually indicates the terminal state of the illness