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Braz. j. med. biol. res ; 23(6/7): 519-23, 1990. ilus
Artigo em Inglês | LILACS | ID: lil-92196

RESUMO

Zinc ions have been reported to stabilize cellular membranes, protecting the gastric mucosa against a wide variety of ulcerative agents. The treatment with zinc sulfate intragastrically administered as one dose (20 mg/Kg body weight) daily for 30 consecutive days did not modify the normal aspect of rat gastric mucosa as observed by electron sanning microscopy. Furthermore, the X-ray microanalysis of the lysosome content performed on different gastric mucosa cells did not show the zinc element. These results suggest that zinc ion is a relatively nontoxic element for the rat gastric mucosa


Assuntos
Animais , Ratos , Masculino , Feminino , Mucosa Gástrica/ultraestrutura , Sulfatos/administração & dosagem , Zinco/administração & dosagem , Zinco/toxicidade , Membrana Celular/efeitos dos fármacos , Ratos Sprague-Dawley
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