1.
Southeast Asian J Trop Med Public Health
;
2003 Jun; 34(2): 415-9
Artigo
em Inglês
| IMSEAR
| ID: sea-35128
RESUMO
We report a case of beta-thalassemia/Hb Tak compound heterozygote. The 7 year-old Thai boy presented with plethora since birth. Hemoglobin electrophoresis showed a major band between Hb A2 and Hb F and absent Hb A. DNA sequencing study demonstrated an AC insertion at the terminal codon of the beta-globin gene. The clinical feature of polycythemia reflected a high oxygen affinity of Hb Tak.