RESUMO
Thirty completely edentulous male subjects, with no previous denture experience, participated in this study. The patients were divided into three groups. The maxillary dentures of group 1 [The control group] as well as the lower dentures of all groups, were constructed from conventional heat-cured acrylic resin. On the other hand, the maxillary dentures of groups II, III were lined with resilient lining inaterials super- soft for group II, and soft liner for group ill. Before denture Insertion, the palatal mucosa of all patients was sampled using the swab culture technique, to detect the presence of Candida albicans. One month, three months and six months after denture adjustment, the fitting surface of the maxillary dentures was similarly sampled using the same culture technique. The models were cultured at 37[degree]c for 48 hours after which the resulting colonies were counted and C. albicans was identified by Germ tube test and API 20C AUX Yeast Identification System. Each time the maxillary dentures were sampled, the clinical appearance. of the palatal denture bearing mucosa and the condition of the resilient denture liners were assessed. The results obtained from this study deduced that super- soft lining material has a less affinity to C. albicans colonization, the best color stability and the least frequency of inflammatory reactions of the underlying mucosa, compared to soft liner lining material. Conventional heat-cured acrylic resin has the least affinity to C. albicans colonization
Conclusion: from the results obtained in this study, the. Following conclusions could be drawn: 1- Both conventional and soft lined dentures have the potentiality to support Candida albicans growth. 2- The affinity of soft liner resilient denture liner for C. albicans colonization is significantly higher than that of super soft liner and relatively higher than that of conventional denture base resin
RESUMO
A series of 40 females complaining of infiltrating duct carcinoma was included in this study. Clinicopathological background, histological grade and immunohistochemical staining for p53, HER-2/neu as well as estrogen and progesterone receptors were analyzed. The results showed that 14 cases were positive to p53, 12 were positive to HER-2/neu, 30 were positive to estrogen receptor and 22 were positive to progesterone receptors. The statistical analysis showed a positive correlation between p53 protein staining with tumor grade and an invasive relation to the hormonal status; whereas, HER-2/neu showed a significant correlation to the lymph node status. No correlation was detected between p53 protein, HER-2/neu protein expression and progression free survival. HER-2/neu protein-positive patients showed an improved response to anthracycline-containing regimen. A complete response was attained in 5% of the cases, partial response in 25%, stationary disease in 60% and 10% of the cases had progressive course