1.
Academic Journal of Second Military Medical University
;
(12): 725-726, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-840574
RESUMO
Protease activated receptor-2 (PAR-2) is a G-protein-coupled receptor. Recent studies indicate that PAR-2 is mainly expressed in leukocytes and activated by pancreatin and (or) tryptase, which subsequently induces inflammation through degranulation of leukocytes. Activation of PAR-2 in leukocytes is possibly involved in the pathogenesis of rheumatoid arthritis.