Long term survival in breast carcinoma

One hundred and six previously treated patients, with breast carcinoma were studied from 1136 breast carcinoma cases attended the clinical oncology and nuclear medicine department, Mansoura university in the period from January 1991 till December 1995 inclusive. These 106 cases were followed up till december 2000. The aim of the study is to evaluate the results of different treatment modalities and assessment of different prognostic factors on recurrence rate [R.R] and recurrence free survival rate [R.F.S]. In both stages II and III, R.R was less and R.F.S was mere in the group received adjuvant chemotherapy or tamoxifen in comparison to the group did not receive adjuvant systemic treatment. Recurrence rate was less and recurrence free survival was more in the group with negative lymph nodes compared to the group with positive lymph nodes. The same results was found in evaluation the value of tamoxifen. Recurrence rate was found less in patients with grade I tumour in comparison with group with grade II or III. Also R.R. was less and R.F.S was more in cases with less number of positive lymph nodes

Gut ischaemia and oxidative stress in pneumo - peritoneum experimental study

One hundred and fifty rats were used in this study and divided into five equal groups [A, B, C, D and E] and a control group and each group was subdivided into three equal subgroups. From the results obtained it was concluded that with pneumoperitoneum, there is an evidence of gut ischemic and oxidative stress. Pneumoperitoneum for less than two hours at a pressure of 15 mmHg or less had no long lasting harmful effect. Pneumoperitoneum for more than three hours at a pressure of 15 mmHg or pneumoperitoneum for less than two hours and a pressure of more than 15 mmHg was harmful. These changes should be considered during laparoscopic surgery