RESUMO
The immobilization of bacillus spp. GU215 on silicon polymer beads, wood chips was performed and antibiotic peptide [bacitracin] production, optimization of parameters were investigated. The immobilized cells presented elevated levels of activity than free cells. The silicon polymer based cells showed widest zones of inhibitions [18mm] in 72 hours and 4% concentration of glucose, PH 8 and 30°C, whereas a marginal decrease in the activity [14mm] was noticed in case of wood chips based immobilization systems and least stable immobilization in 72 hours incubation time, 4% glucose concentration, PH 8 and 30°C. This study illustrates that the silicon polymer based beads facilitate a strong interactions with bacitracin producing cells and render them suitable for excessive and long time production of antibiotic