RESUMO
Influence of stem extract of banana (family Musaceae), was studied on glycolic acid oxidase (GAO) and lactate dehydrogenase enzymes, calcium, phosphorus, oxalate and glycolic acid in liver tissues of sodium glycolate-induced hyperoxaluric rats. Activity of GAO was significantly lowered in the extract-treated rats compared to that of the glycolate-fed rats. LDH increased significantly in glycolate administered rats when compared with the extract-treated rats. The levels of calcium, phosphorus, oxalate and glycolic acid during hyperoxaluric state showed remarkable alterations in liver tissue.
Assuntos
Oxirredutases do Álcool/análise , Animais , Cálcio/análise , Frutas , Glicolatos/análise , Hiperoxalúria/induzido quimicamente , L-Lactato Desidrogenase/análise , Fígado/química , Masculino , Oxalatos/análise , Ácido Oxálico , Fósforo/análise , Extratos Vegetais/farmacologia , Ratos , Ratos WistarRESUMO
Influence of L(+)-tartrate was studied on certain enzymes, protein bound carbohydrates and lipids in the renal tissues of experimentally induced stone forming rats. The elevation in kidney LDH was moderate in the stone forming groups while tartrate had no effect. The significant increases in the activities of (Na+, K+)- and (Ca2+)-ATPases in the calculogenic group was lowered to that of normal level with tartrate administration. Acid phosphatase activity was significantly lowered in the tartrate treated groups. The significant reduction in phospholipids and elevation in sialic acid levels during stone formation are suggestive of minor alterations in the cellular structure. The changes in the transport ATPases is likely to affect the transport mechanism of nutrients and ions.