1.
Egyptian Journal of Chemistry. 2009; 52 (3): 349-360
em Inglês
| IMEMR
| ID: emr-135688
RESUMO
This work concerns with studying the reaction of cyanoacetyl hydrazide with cyclopentanone to give the hydrazide-hydrazone derivative 3. The reactivity of compound 3 towards different chemical reagents was studied to give coumarin, pyridine and thiazole derivatives. The antimicrobial evaluation of the synthesized products was studied where most of them showed interesting activities
Assuntos
Piridinas/síntese química , Tiazóis/síntese química , Nitrilas/farmacologia , Ciclopentanos/farmacologia
2.
Egyptian Journal of Chemistry. 2001; 44 (4-6): 315-333
em Inglês
| IMEMR
| ID: emr-56693
RESUMO
The reaction of benzoyl acetonitrile [1] with acetoacetanilide derivatives 2a-c gave the acyclic products 3a-c, respectively. The reaction of 3a with hydrazines, urea, thiourea, aromatic aldehydes and malononitrile gave pyrazole, pyrimidine, pyrazolo [3,4-d] pyridine and pyrido [2,3-d] pyrimidine and pyridine derivatives