RESUMO
<p><b>OBJECTIVE</b>To investigate the effects of long time cruising on fishermen' immune function and nutrition state.</p><p><b>METHODS</b>Thirty-two fishermen's lymphocyte subsets, immunoglobulin, alexin, prealbumin, albumin, blood fat, hemoglobin serum iron, transferrin were tested before and after cruising.</p><p><b>RESULTS</b>The expression of CD-19 was significantly higher after cruising (P < 0.001) while other cell immune functions were not significantly changed. After cruising, the immunoglobulin IgG, IgA, alexin C3, B, prealbumin, albumin, transferrin were higher than before cruising (P < 0.001). HDL-C was higher (P < 0.05); Apo-B, and serum iron were lower (P < 0.01).</p><p><b>CONCLUSION</b>The cruising fishermen' immune function is changed significantly; the nutrition state is good, but the serum iron is insufficient and in subclinical state.</p>