1.
LMJ-Lebanese Medical Journal. 1998; 46 (1): 16-9
em Inglês
| IMEMR
| ID: emr-122171
RESUMO
We report the results of karyotype analysis on cases referred to our laboratory for chronic myelogenous leukemia [CML] over a period of three years. A total of 68 patients were referred and a karyotype was successfully obtained in all cases except one. Thirty one percent of cases were found to have a normal karyotype, 58.5% were Philadelphia [ph1] positive while 10.5% of cases had chromosome abnormalities other than ph1. among the ph1 positive cases, 92% had the standard translocation [9;22], 7.7% had a variant translocation and 12.8% had additional chromosome abnormalities. Our results are compared to those generally reported in the literature and the comparisons are discussed