The Effect of Urokinase on the Hyphema in Rabbits

In 20 eyes of 10 rabbits, total hyphema were produced by injecting human fresh blood into the anterior chamber after aspirating the aquous humor. six hours later, 10 left eyes of them were treated with injection of urokinase into the anterior chamber. A control group of 5 right eyes were treated with normal saline and the other 5 right eyes were left untreated. The eyes treated with urokinase showed the most rapid rate of absorption of blood clot and clearance of corneal opacity among 3 groups. The comparison between the group treated with normal saline and the untreated group about the absorption rate of blood clot and clearance of corneal opacity were made. The former is slightly rapid than the later, but there was no significant differance between them. The observation of ciliary injection and changes of intraocular pressure had not shown a significant differance among 3 groups.

A Clinical Study of Vistamycin in Ophthalmology

Vistamycin is a new type of aminoglycoside antibiotics and similar to Kanamycin in its antibacterial spectrum. Vistamycin is especially effective in ophthalmic field due to high penetration into the ocular tissue. In this study, the patients were divided into three groups. 1. 13 cases of ocular infectious diseases such as hordeolum and dacryocystitis. They have received intramuscular injections. 2. 32 cases receiving intramuscular injection for prophylaxis of postoperative infection. 3. 5 cases receiving topical application of 1% Vistamycin eye-drops. Group 1 and 2 were treated with intramuscular injection of Vistamycin 1.0 G.per day for 2 to 10 days. The results were summerized as follows: (1) Group 1 showed good response to Vistamycin with about 77% of efficacy rate. (2) None of group 2 developed postoperative infection. (3) The efficacy rate of group 3 was about 80%.

The Effects of the Tranquilizers on Heterophoria

In 54 cases with heterophoria, the effects of the tranquilizers were studied. The minimum doses of two kinds of tranquilizers i.e., phenothiazine derivative (chlorpromazine) and benzodiazepine derivative (oxazepam) were given for 3 days. The results were as follows: 1. In 18 cases (43%) of the 30 cases who complained asthenopia, the symptom was relieved to some extent. The improvement of the symptom occurred with decrease in the Jateral phoria in 13 cases, and with increase in fusional amplitude in 13 cases. 2, There were no changes in the lateral phoria in 31 cases (59%) at distance, but at near, in 27 cases (52%) there was decrease in the lateral phoria. The amount of the increment or decrement in prism diopters was somewhat larger at near than at distance, and also somewhat larger in cases, in which the initial lateral phoria before medication is high, than in the cases with low initial lateral phoria. 3, There were no changes in the fusional amplitude in 24 cases (46%) at distance, but at near, in 28 cases (55 %) there was the increase in fusional amplitude. The changes in the amount of the increment or decrement in the fusional al1}plitude were similar to that of the changes in the amount in lateral phoria. 4, There were no remarkable changes in vertical phorias. 5. In exophoria there were no remarkable differences between subjects given chlorpromazine and those gIven oxazepam.

Statistical Observations on the Vascular Changes in Hypertensives

No abstract available.

The Effect of Rauwolfia Serpentina on the Retinal Arterial Blood Pressure in Hypertensive Patients

The diastolic retinal arterial blood pressure was measured by Ophthalmodynamometer in 15 patients of essential hypertension before and after the administration of Raudixin three times a days. The follow up period was 4 to 70 days. The average fall of the systolic brachial blood pressure was 38.1 mmHg(from 174.6 to 136.5 mmHg) 19 days after the treatment, whereas the average fall of the diastolic brachial blood pressure was 19.6 mmHg (from 166.6 to 94.7 mmHg) 24 days after treatment. A positive correlation was demonstrated between the retinal and brachial diastolic blood pressures prior to the treatment. The diastolic brachial blood pressure showed its fall only 15 days after treatment, the average fall being 17.1 mmHg. During this period of time, the average fall of the diastolic retinal arterial pressure was 10.2 mmHg. In 6 cases, the retinal arterial pressure didn't fall back to the normal valures and in 5 cases of Keith-Wagener group II, the retinal arterial pressure remained unchanged in spite of the treatment. The percentage ratio of the retinal to the brachial diastolic blood pressure remained stationary in 3 cases, rose in 4 cases. The number of cases which show fall in this ratio gradually increased and about 80% of the cases demonstrated definite fall one month after treatment. The retinal arterial pressure remained stationary during 2 weeks after treatment in 60% of the cases. The significant lowering of the retinal arterial blood pressure was observed only one month after treatment in the majority of cases. The retinal arterial pressure fell below normal range in no case.