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1.
Chinese Journal of Medical Science Research Management ; (4): 178-181, 2023.
Artigo em Chinês | WPRIM | ID: wpr-995852

RESUMO

Objective:This stndy aims to analyze the influence of ChatGPT on medical research and give suggestions on GhatGPT.Methods:This paper expounded the background of ChatGPT, analyze the connection between ChatGPT and medical research management, application and threats of ChatGPT , and gave suggestions to avoid GhatGPT′s damage.Results:Technology will promote the evolution of medical research management. It is recommended to strengthen the supervision of the ChatGPT and research integrity education.Conclusions:It is urgent to establish a scientific management mechanism to take usage the advantages of GhatGPT.

2.
Chinese Journal of Natural Medicines (English Ed.) ; (6): 916-926, 2023.
Artigo em Inglês | WPRIM | ID: wpr-1011003

RESUMO

Natural products are essential sources of antitumor drugs. One such molecule, β-elemene, is a potent antitumor compound extracted from Curcuma wenyujin. In the present investigation, a series of novel 13,14-disubstituted nitric oxide (NO)-donor β-elemene derivatives were designed, with β-elemene as the foundational compound, and subsequently synthesized to evaluate their therapeutic potential against leukemia. Notably, the derivative labeled as compound 13d demonstrated a potent anti-proliferative activity against the K562 cell line, with a high NO release. In vivo studies indicated that compound 13d could effectively inhibit tumor growth, exhibiting no discernible toxic manifestations. Specifically, a significant tumor growth inhibition rate of 62.9% was observed in the K562 xenograft tumor mouse model. The accumulated data propound the potential therapeutic application of compound 13d in the management of leukemia.


Assuntos
Humanos , Camundongos , Animais , Linhagem Celular Tumoral , Doadores de Óxido Nítrico/farmacologia , Sesquiterpenos/farmacologia , Leucemia/tratamento farmacológico , Bioensaio , Proliferação de Células
3.
Chinese Critical Care Medicine ; (12): 294-300, 2020.
Artigo em Chinês | WPRIM | ID: wpr-866823

RESUMO

Objective:To understand the current situation of research in the field of sepsis caused by Gram positive bacteria (G + bacteria) in China, to clarify the research content and analyze its general research direction, so as to find the hot topics of research in recent years. Methods:The literatures in SinoMed related to sepsis caused by G + bacteria and published in Chinese from building database to October 2019 were screened. The distribution and trend of the published year, journals, research institutions and researchers of relevant literature were analyzed, and Ucinet 6.0 software was used to draw the social network graph of the researchers and to analyze their internal relations. The subject words of related literatures were extracted. The relationship among the subject words in related literatures was arranged according to the centrality by NetDraw in Ucinet 6.0 software, the bibliographic information co-occurrence analysis system software (BICOMS2 software) was used to classify the subject words and the visualization matrix was generated. The graph clustering tool software (gCLUTO software) was used to cluster the subject words, and the visualization surface graph was generated to analyze the current research hot spot, research trend and research direction of G + bacteria-induced sepsis. Results:A total of 1 976 literatures about sepsis caused by G + bacteria were retrieved, and 26 literatures in conference summaries, news reports, research information, missing content, or inconsistent with the theme were excluded. Finally, a total of 1 950 literatures were enrolled in final analysis. The number of published literatures analysis showed that from 1979 to 1992, there were few studies about sepsis caused by G + bacteria, which increased geometrically from 2008, and the number of literatures published from 2008 to 2018 was 1 144, accounting for 58.67% (1 144/1 950). From 1979 to 2019, 23 high-yield institutions published more than 5 literatures, of which 6 were institutions with 10 or more literatures, and only one institution with more than 20 literatures. There were only 5 journals with more than 100 articles, 5 381 authors involved in the literatures, but few authors with more than 10 literatures published, and no inter-provincial or inter-municipal cooperation was found. A social network analysis of 103 high-frequency subject words that appeared more than 5 times showed that the study of sepsis caused by G + bacteria mainly focused on "sepsis", including the incidence of sepsis caused by drug resistant Staphylococcus aureus was on the rise, especially in newborns and children with weakened immune systems, the selection of therapeutic drugs gradually developed to glycopeptides with strong anti-drug resistance and synthetic oxazolidinones. The research and development of drugs for the treatment of sepsis caused by G + bacteria might become a new research direction or field in the future. Cluster analysis of 103 high-frequency subject words showed that the research hot spots of G + bacteria-induced sepsis mainly focused on five topics, namely early diagnosis of sepsis; bacterial infection pathway of sepsis, nosocomial infection and bacterial drug resistance; the basis of epidemiological prevention and treatment of sepsis; venous catheter infection-related sepsis; the treatment, nursing and prognosis of patients with sepsis. Conclusion:The studies of sepsis caused by G + bacteria are winning more and more attention, but the resources sharing and academic exchanges among hospitals need to be further improved.

4.
Chinese Journal of Medical Science Research Management ; (4): 293-298, 2020.
Artigo em Chinês | WPRIM | ID: wpr-872069

RESUMO

Objective:To construct a scientific research performance evaluation index system for specialized hospitals based on disciplinary development.Methods:Building a preliminary evaluation index framework of scientific research performance through literature review and expert consultation meetings, combined with the strategic goals of strengthening specialization and weakening generalization; Delphi method was adopted to conduct two rounds questionnaires survey to collect the importance scores for each index, which confirmed the content of the index system; finally, applied the analytic hierarchy process to calculate the weight coefficient of each index.Results:The responding rates of the two rounds questionnaire survey reached 95%, and the authoritative coefficients were 0.75 and 0.76, respectively. The research results were reliable. The coordination coefficients of all levels of the two surveys were greater than 0.1, according to the significance testing, the P values were less than 0.05, and the expert opinions were well coordinated. Finally, we developed a three-level scientific research performance evaluation system under the guidance of disciplinary development, which including 3 first-level indicators, 20 second-level indicators, as well as 56 third-level indicators. Conclusions:A scientific research performance evaluation system was constructed based on scientific theories. This system combined relevant indicators, such as the development of special disciplinary of specialized hospitals with scientific validity and operability. Besides, it could serve as a tool to evaluate the scientific research performance of specialized hospitals taking into account of the practical application value for guiding scientific research development and disciplinary improvement.

5.
Chinese Mental Health Journal ; (12): 1-6, 2018.
Artigo em Chinês | WPRIM | ID: wpr-703972

RESUMO

Objective:To explore the characteristics of the social cognition in patients with high/low functioning early onset schizophrenia (HF-EOS).Methods:Eighty-four 13-18 years old patients with early onset schizophrenia and 45 gender-,age-,and level of education-matched healthy controls (HC) were selected.The diagnosis was made according to the criteria of the International Statistical Classification of Diseases and Related Health Prob lem,Tenth Revision (ICD-10) for schizophrenia.All patients were divided into HF-EOS group (total score > 7,n =41) and LF-EOS group (total score < 4,n =43)in the three aspects total score of social attainment,social compe tence and functional capacity.All patients were assessed with the Eye Basic Emotion Discrimination Task,Reading the Mind in the eyes,Yoni task and Faux Pas Recognition task.Results:Compared with healthy controls,LF-EOS patients performed poorer on Reading the Mind in the eyes task [(17 ± 4) vs.(9 ± 3.0),P < 0.05],second-order cognitive condition of the Yoni task [(71 ± 18) vs.(83 ± 13),P < 0.01] and Recognizing Faux pas [(8 ± 2) vs.(9 ± 2),P <0.05].HF-EOS and LF-EOS patients performed worse than the controls on second-order affective condition of the Yoni task [(80 ± 14),(75 ± 15) vs.(86.5 ± 10.0),P < 0.01] and understanding paux pas [(17 ± 5),(14 ± 5) vs.(21 ± 6),P < 0.01].Conclusion:It suggests that HF-EOS have preserved social perceptual abilities compared to LF-EOS patients.HF-EOS patients and LF-EOS patients both have impaired theory of mind compared to controls.

6.
Chinese Journal of Medical Ultrasound (Electronic Edition) ; (12): 512-518, 2017.
Artigo em Chinês | WPRIM | ID: wpr-669264

RESUMO

Objective To investigate the value of quantitative analysis of the left ventricular longitudinal strain in patients with hypertrophic cardiomyopathy (HCM) and with normal left ventricular ejection fraction (LVEF) by using two-dimensional speckle tracking imaging.Methods Twenty-eight HCM patients with normal LVEF (all of the cases were non obstructive HCM),who were diagnosed by clinical and ultrasound echocardiography between January 1,2015 and January 1,2016 in the First Affiliated Hospital of Dalian Medical University,served as the experimental group.And twenty healthy volunteers served as the healthy control group.The peak longitudinal strain (LPS) of the left ventricle and the systolic peak of the left ventricle were calculated by the STE technique.The indexes such as the transmural gradient (△ LS=LPSEndo-LPSEpi)and the transmural gradient percentage (△ LS%=△ LS/LPSEndo) were calculated.The Peak systolic longitudinal strain of endocardium (LPSEndo),the peak systolic longitudinal strain of mid-cardium (LPSMid),the peak systolic longitudinal strain of epicardium (LPSEpi),the peak systolic longitudinal strain of basal segment (LPSb),the peak systolic longitudinal strain of middle segment (LPSm),the peak systolic longitudinal strain of apical segment (LPSa),the global peak systolic longitudinal strain (GLPS) and other left ventricular myocardial strain,such as △ LS,△ LS%,in both the HCM group and the healthy control group,were analyzed by using independent samples t test comparison.For each layer of the left ventricle and the overall myocardial longitudinal strain,two independent sample t test was used for comparison between groups,and LSD-t test was used for intra-group comparison.Results (1) There was a gradient of LPS among the three layers and the three segments in both of the two groups:LPSEndo and LPSMid [(18.36±4.97)% vs (13.80±4.23)%,(26.41±2.93)% vs (22.19±2.49)%],the difference was statistically significant (t=5.550,8.529,P < 0.05);LPSEndo and LPSEpi [(18.36±4.97) % vs (11.91 ±3.63)%,(26.41±2.93)% vs (19.43±2.20)%],the difference was statistically significant (t=5.550,8.529,P < 0.05);There was significant difference between LPSMid and LPSEpi in the healthy control group [(22.19 ± 2.49)% vs (19.43 ± 2.20)%,t=3.709,P < 0.05)],that was,LPSEndo > LPSMid > LPSEpi.LPSa and LPSm,the difference was statistically significant (t=4.029,6.839,P < 0.05);LPSa and LPSb,the difference was statistically significant (t=5.304,9.887,P < 0.05);There was significant difference between LPSm and LPSb in the healthy control group (t=4.170,P < 0.05);that was,LPSa > LPSm > LPSb.In the HCM group,LPS in the 3 layers,3 segments,and the whole left ventricular wall were lower than that of the the healthy control group,the differences were statistically significant [GLPS:(14.63± 3.75)% vs (22.68±2.51)%,t=-8.347;LPSEndo to LPSEpi:t=-6.477,-7.909,-8.242;LPSa to LPSb:t=-6.647,-8.790,-7.267;all P < 0.05).(2) Compared with the healthy control group,both the segmental gradient and global transmural gradient in the HCM group were found reduced,but the difference had no statistical significance (all P > 0.05).(3) The transmural gradient percentage both in the healthy control group and the HCM group were reduced from the apical segment to the basal segment,the difference were statistically significant (HCM group:t=9.985,5.969;healthy control group:t=17.513,7.043;all P < 0.05).Compared with the healthy control group,the △ LS%a and the △ LS%m of HCM group were significantly higher [(58.86± 11.32)% vs (43.70±4.73)%,(28.43± 11.48)% vs (20.30± 3.66)%],and the difference was statistically significant (t=5.634,3.049,all P < 0.05).Conclusions (1) Using 2D-STI could accurately determine the regional or the global left ventricular systolic function in patients with HCM.(2) The transmural gradient percentage can be more sensitive to reflect the change of the transmural gradient,and more research needed to explore its value for clinical application.

7.
Chinese Journal of Practical Nursing ; (36): 412-415, 2016.
Artigo em Chinês | WPRIM | ID: wpr-488283

RESUMO

Objective To investigate the fall efficacy of elderly people in nursing homes and its influencing factors. Methods A total of 174 elderly people in 8 nursing homes in Fujian province were recruited by convenience sampling method. They were investigated with a self-designed questionnaire about the demographic data, the Modified Falls Efficacy Scale (MFES) and the Kessler Psychological Distress Scale (K10). Results The mean score of fall efficacy was 7.81±1.15, which revealed a middle level. The score of get dressed and undressed scored 9.04 ±1.42, which was the highest, while the score of using public transport scored 5.80 ±3.21, which was the lowest. Multiple regression analysis showed that the mental health status, degree of self care, age were influencing factors of fall efficacy of elderly people. Conclusions The fall efficacy level of 174 elderly people is at medium level, which is different among fall efficacy with mental health status, degree of self care, age. Individualized interventions should be designed and provided for them.

8.
China Pharmacy ; (12): 2689-2691, 2015.
Artigo em Chinês | WPRIM | ID: wpr-500934

RESUMO

OBJECTIVE:To establish a new semi-automatic drug dispensing mode,with proper cost,which falls in between full-automatic drug dispensing mode and manual drug dispensing mode,good work efficiency,standard and simple operation meth-od and meets national laws and regulations. METHODS:A semi-automatic drug dispensing system was designed,in which the in-formation in the drug dispensing sheet could be automatically printed on the drug bag,and automatic bagging,packaging and deliv-ery of drugs were realized. Such drug dispensing system included hardware(mechanical structures such as drug turntable and drug funnel,transmission device,etc.)and software control systems(the program of interface with hospital information system,micro control unit software,computer software,etc.). Through commissioning,formal operation and statistics,based on 18 oral drug dis-pensing sheets with the same contents,calculated the time of drug dispensing and the number of drug dispensing errors by 3 phar-macists respectively in manual drug bag dispensing mode and semi-automatic drug dispensing mode,to evaluate the effect of the semi-automatic drug dispensing system. RESULTS:From commissioning in May 2012 to formal operation in September 2012,the system operated normally and utility model patents were obtained. In the two modes,the total time of drug dispensing was 481 and 397 min (t=6.82,P<0.001),the numbers of drug dispensing errors were 25 and 7 (χ2=9.353 8,P=0.002 2),respectively. There was statistical significance. CONCLUSIONS:The semi-automatic drug dispensing system has higher efficiency and less num-ber of drug dispensing errors compared with manual drug bag dispensing mode and lower cost compared to full-automatic drug dis-pensing system. It deserves promotion.

9.
Chinese Journal of Trauma ; (12): 735-739, 2014.
Artigo em Chinês | WPRIM | ID: wpr-454071

RESUMO

Objective To investigate the effect of dopamine receptor in intestinal mucosal barrier function after brain injury in rats.Methods Twenty-four rats were allocated to control group,brain injury group,dopamine receptor group,and dopamine antagonist group according to the random number table,with 6 rats per group.Feeney' s weight-drop model was introduced to generate rat models of brain injury.Intestinal mucosal specimens were harvested at postoperative 7 days to evaluate intestinal mucosal morphology by HE staining,expressions of dopamine receptor D1 (DRD1) and dopamine receptor D2 (DRD2) by immunohistochemistry,and mRNA and protein expressions of DRD1 and DRD2 by real-time PCR and Western blot.Meantime,urinary samples were collected to measure lactulose to mannitol ratio (L/M) by high performance liquid chromatography (HPLC).Results Intestinal villus integrity was disrupted in brain injury group and dopamine receptor group when compared to control group,but it remained relatively intact in dopamine antagonist group.Ratio of L/M in brain injury group and dopamine receptor group was similar (0.192 ± 0.080 vs 0.183 ± 0.090,P > 0.05),far higher than 0.037 ± 0.008 in control group (P <0.01),but it was reversed in dopamine antagonist group (0.071 ± 0.008,P < 0.01).Real-time PCR showed DRD1 and DRD2 mRNAs expressed in brain injury group and dopamine receptor group were similar (0.764 ± 0.074 vs 0.718 ± 0.065,0.439 ± 0.051 vs 0.408 ± 0.090,P > 0.05),far higher than 0.189 ± 0.008 and 0.076 ± 0.011 in control group (P < 0.01),but both lowered in dopamine antagonist group (0.386 ± 0.071,0.270 ± 0.092,P < 0.01).estern blot analysis showed DRD1 and DRD2 proteins in brain injury group and dopamine receptor group were similar,but both were far higher when compared to control group (P < 0.01).Conclusion Impaired intestinal mucosal barrier may be relate to the up-regulated dopamine receptor in intestinal mucosa after brain injury in rats.

10.
Chinese Journal of Anesthesiology ; (12): 491-493, 2011.
Artigo em Chinês | WPRIM | ID: wpr-416869

RESUMO

Objective To investigate the effects of δ-opioid receptor agonist DADLE (D-Ala2-D-Leu5-enkephalin) on the hemodynamics and oxygen metabolism in rats with sepsis. Methods Eighty healthy male SD rats were randomly divided into 4 groups ( n = 20 each) : sham operation group (group S), sepsis group (group SEP) ,DADLE, group and DADLE2, group. Sepsis was induced by cecum ligation and puncture (CLP) in SEP, DADLE,and DADLE2 groups. In DADLE1 and DADLE2 groups, 0.5 mg/ml DADLE 10 mg/kg was injected intraperitoneally (IP) 0.5 h before CLP and immediately after CLP respectively. Mean arterial pressure (MAP), left ventricular systolic pressure (LVSP) and ± dp/dtmax were recorded at 0, 2, 4 and 6 h after CLP (T1-4). Blood samples from left common carotid artery and right external jugular vein were collected at T4 for blood gas analysis. The cardiac index (CI), O2 delivery (DO2), O2 consumption (VO2) and O2 extraction rate (ERO2) were calculated.Results Compared with group S, MAP and LVSP were significantly increased at T2, while decreased at T3,4, and ± dp/dtmax was significantly increased in group SEP, MAP was significantly increased at T2, while decreased at T3,4, LVSP was significantly increased at T2,3, while decreased at T4 , and ± dp/dtmax was significantly increased in DADLE, and DADLE2 groups, and CI, DO2 and VO2 were significantly decreased and ERO2 was increased in SEP, DADLE, and DADLE2 groups (P<0.05). Compared with group SEP, MAP, LVSP and ± dp/dtmax at T3,4 and CI, DO2 and VO2 were significantly increased, while ERO2 was significantly decreased in DADLE1 and DADLE2 groups (P < 0.05). There was no significant difference in the parameters mentioned above between DADLE1 and DADLE2 groups ( P > 0.05). Conclusion δ-opioid receptor agonist DADLE can obviously improve the hemodynamics and oxygen metabolism in septic rats.

11.
Chinese Journal of Practical Nursing ; (36): 1-4, 2010.
Artigo em Chinês | WPRIM | ID: wpr-390330

RESUMO

Objective To analyze the professional psychological pressure and coping style of male nursing students during different learning stage,and discuss effective ways to solve these problems in order to promote physical and mental health development of male nursing students.Methods Using coping style questionnaire and the professional psychological pressure of nursing students questionnaire to survey 102 undergraduate male nursing students from grade 2005 to 2008 of a nursing college of certain province.Results The professional psychological pressure of undergraduate male nursing students was moderate.Male nursing students of different grades had different professional pressure,in which male nursing students of secondyear had lower professional psychological pressure than other students.Manners they adopted to cope with pressure were mature,that is,the "problem-solving-help" approach,in which ways taken by second-year students were more than others.Conclusions Social bias to male nurses should be corrected.Professional psychological education should be carried out to relieve their mental pressure according to characteristics of students in different stage and direct them to realize role change.

12.
Chinese Journal of Practical Nursing ; (36): 1-4, 2010.
Artigo em Chinês | WPRIM | ID: wpr-388608

RESUMO

Objective To evaluate the quality of life and care needs of hospitalized AIDS patients and analyze the relationship between them to provide basis for clinic nurses' helping patients to improve the quality of life. Methods We adopted the general information questionnaire, patient care needs assessment questionnaire, as well as the World Health Organization Quality of life Scale (WHOQOL)and used cluster sampling method to make face to face interviews with 36 hospitalized AIDS patients. Results The care needs of the 36 AIDS patients were at a high level,all areas of quality of life were lower than the norm. The quality of life of hospitalized AIDS patients was negatively correlated with the care needs. Conclusions Clinic nursing staffs should understand and assess the care needs of patients initiatively and take appropriate measures to improve quality of life of hospitalized AIDS patients.

13.
Chinese Journal of Anesthesiology ; (12): 878-880, 2010.
Artigo em Chinês | WPRIM | ID: wpr-385904

RESUMO

Objective To investigate the effect of δ-opioid receptor agonist D-Ala2-D-Leu5-enkephalin (DADLE) on the celluar immune function in septic rats. Methods One hundred and fifty healthy male SD rats weighing 154-198 g were randomly divided into 3 groups (n = 50 each):group Ⅰ sham operation (group S);group Ⅱ sepsis (group SEP) and group Ⅲ DADLE. Sepsis was induced by cecum ligation and punture (CLP) in group Ⅱ and Ⅲ. In group Ⅲ 0.5 rmg/kg DADLE 10 ml/kg was injected intraperitoneally (IP) immediately after CLP operation. Seven day survival rate was calculated. Blood samples were collected from 10 animals at 4, 8 and 12 h after operation (T1-3) respectively in each group for determination of serum TNF-α and IL-10 concentrations by ELISA and changes in T-cell subsets by flow cytometry. Results CLP significantly increased serum TNF-α and IL-10 concentrations and TNF-α/IL-10 ratio at T1-3 and decreased CD4+ and CD4+/CD8+ ratio and increased CD8+ at T3 in group Ⅱ as compared with group S (group Ⅰ). DADLE treatment significantly attenuated the CLP-induced above changes. Seven-day survival rate was significantly higher in DADLE group than in CLP group.Conclusion δ-opioid receptor agonist DADLE can improve the celluar immune function of rats with sepsis and increase the survival rate.

14.
Chinese Journal of Practical Nursing ; (36): 4-8, 2009.
Artigo em Chinês | WPRIM | ID: wpr-393406

RESUMO

Objective To explore the psychological feelings of inpatients with AIDS, direct nurses to understand their psychological feelings in order to provide holistic nursing care. Methods Phenomenological method in qualitative research was adopted, 12 inpatients with AIDS were interviewed. Results The emo-tional feelings of inpatients with AIDS concerned mainly about: feeling shocked when they got to know they had affected with AIDS, wanting to commit suicide because of suffering, earnestly demanding for the com-panion of family members, the need for mental supports, planning to go on to work after feeling better be-cause of financial problems, worrying about children at home. Conclusions Nurses should estimate the changes in emotional reactions of inpatients with AIDS properly, understand their life conditions, and help them to promote their life quality by providing holistic nursing care.

15.
Chinese Journal of Practical Nursing ; (36): 18-21, 2009.
Artigo em Chinês | WPRIM | ID: wpr-391802

RESUMO

Objective To explore the effects of exercise nursing intervention on renal transplant recipients.Methods A convenient sample of 64 renal transplant recipients during rehabilitation period were divided into the experimental group and the control group with 32 cases in each group.The experimental group received routine care and rehabilitation exercise,while the control group just received routine care.The body mass index(BMI),blood pressure and heart rate were measured in the two groups.Results Before intervention the differences of BMI,heart rate,blood pressure between the two groups were not statistically significant.However,after intervention,the BMI and blood pressure of the experimental group were lower than those of the control group,but there was no significant differences in heart rate.Conclusions Rehabilitation exercise nursing intervention contributes to raise recipients' quality of life and promote whole rehabilitation.

16.
Chinese Journal of Practical Nursing ; (36): 1-2, 2008.
Artigo em Chinês | WPRIM | ID: wpr-401657

RESUMO

Objective To study the correlation between social support for nurses and patients'satisfaction degree with nursing work.Methods The social support for nurses was evaluated by Xiao Shui-yuan's Social Support Rate Scale(SSRS).The patients'satisfaction degree with nursing work was assessed by self-designed inventory.Results The three dimensions of social support and its total score were positively correlated with patients'satisfaction degree(r=0.21~0.32).Not only the subjective support and patients satisfaction degree with nurses's care but also the objective support and patients satisfaction degree with nurses's knowledge and technique was hishly correlated.The correlation also existed in nursess'utilization degree of social support and patients' satisfaction degree with nurses's knowledge and tech-nique.Conclusion The social support for nurses was correlatd with patients'satisfaction degree with nursing work.Dood social support may contribute to alleviated patients'satisfaction degree

17.
Chinese Journal of Practical Nursing ; (36): 6-8, 2008.
Artigo em Chinês | WPRIM | ID: wpr-399769

RESUMO

Objective To study the effect of hospital disposal manners after workplace violence in hos-pital on organizational commitment and turnover intention among the head nurses. Methods Self-made questionnaire about workplace violence in hospital and general condition, organizational commitment question-naire and turnover intention questionnaire were conducted in 122 head nurses who had suffered hospital vio-lence in recent years from all level hospitals of Fujian province. Results The scores of affective commitment and normative commitment of organizational commitment and turnover intention showed significant difference be-tween the groups who suffered positive disposal and who suffered negative interference by the hospital after the violence events (P<0.05), but aggregate score of organizational commitment and the scores of continuance commitment showed no significant difference between the two groups (P>0.05). Hospital disposal manners af-ter the hospital violence and hospital grade were influence factors on turnover intention among the head nurses.Hospital grade was also an influence factor on organizational commitment among the head nurses. Conclu-sions Hospital positive disposal means after the hospital violence on head nurse help to ameliorate organiza-tional commitment and reduce turnover intention among the head nurses.

18.
Chinese Journal of Rehabilitation Theory and Practice ; (12): 175-176, 2007.
Artigo em Chinês | WPRIM | ID: wpr-973591

RESUMO

@#ObjectiveTo investigate the correlation between the interpersonal trust and coping modes in aged patients with coronary heart disease (CHD).MethodsA total of 246 aged patients with CHD at home and in hospital were tested on their interpersonal trust and reply modes by adopting the Interpersonal Trust Scale (ITS) and Medical Coping Modes Questionnaire (MCMQ).ResultsThe interpersonal trust level of patients with higher educational background was significantly higher than those with poor educational background ( P<0.05). The patient's interpersonal trust was significantly positive correlation to the confrontation coping mode ( r=0.388, P=0.000) and significantly negative correlation to the compromising coping mode ( r=-0.434, P=0.000), but was not significantly correlation to avoidance coping mode ( P>0.05).ConclusionThe interpersonal trust of aged patients with CHD can influence their choice of coping modes.

19.
Chinese Journal of Rehabilitation Theory and Practice ; (12): 120-121, 2007.
Artigo em Chinês | WPRIM | ID: wpr-973254

RESUMO

@# ObjectiveTo explore the factors influencing quality of life (QOL) in post-stroke patients.MethodsThe data of 76 first-stroke patients in three general hospitals at 1 month and 4 months after stroke were selected with Stroke Impact Scale and analyzed with multiple linear regression.ResultsThe influencing factors of patients' QOL at one months after stroke were education background, type of care, gender, pathological regions, marriage and complications. The education background was the most important influencing factor. The influencing factors of 4 months after stroke were rehabilitation nursing, marriage, social support and gender. Rehabilitation nursing was the most important influencing factor.ConclusionThe many factors influence QOL for post-stroke patients and are changed with time.

20.
Chinese Journal of Rehabilitation Theory and Practice ; (12): 120-121, 2007.
Artigo em Chinês | WPRIM | ID: wpr-973225

RESUMO

@#ObjectiveTo explore the factors influencing quality of life (QOL) in post-stroke patients.MethodsThe data of 76 first-stroke patients in three general hospitals at 1 month and 4 months after stroke were selected with Stroke Impact Scale and analyzed with multiple linear regression.ResultsThe influencing factors of patients' QOL at one months after stroke were education background, type of care, gender, pathological regions, marriage and complications. The education background was the most important influencing factor. The influencing factors of 4 months after stroke were rehabilitation nursing, marriage, social support and gender. Rehabilitation nursing was the most important influencing factor.ConclusionThe many factors influence QOL for post-stroke patients and are changed with time.

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