Synthesis of polyfunctionally substituted 5,6,7,8 tetrahydroquinolines and several condensed azines

2-amino-3-cyano-4-phenyl-5,6,7,8-tetrahydroquanoline [3] and other related new quinolones were synthesized and submitted to evaluation for their anti-microbial activity. Compound [3] was prepared by reaction of cyclohexanone, arylidines malononitrile and amm. acetate. Other reagents were studied as the nature of the nuceolophile and reaction conditions. The behaviour of some products towards carbon electrophiles, e.g. acid chlorides, acid anhydrides and alkylating agents has been discussed