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Objective To analyze the epidemic characteristics of AIDS, gonorrhea and syphilis from 1990 to 2013 in Huangpu District, Shanghai, and to evaluate the effects of prevention and control in this re-gard. Methods Ecology research method was used to analyze epidemic characteristics of sexually trans-mitted disease. Results From 1990 to 2013, the incidence of gonorrhea increased first and then de-creased in recent years, while that of syphilis had been increasing since 1994, among which latent syphilis was the most.AIDS cases occurred each year from 2006.The young male adults of 25-39 years old were the main population who had these three kinds of sexually transmitted diseases.The cases of AIDS and syphilis were mainly found in those engaged in housekeeping, housework and the unemployed, and gonor-rhea was mostly with workers. Conclusion The incidence of gonorrhea in Huangpu District has been de-creasing, while the prevention and control of AIDS and syphilis still needs to be strengthened.The inci-dence is influenced by the change of people’ s awareness and behavior.In future, we should focus on key groups like young males, housekeeping, unemployed and recurrent population.
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[Objective] To investigate epidemic characteristics of tuberculosis (TB) in Huangpu District of Shanghai, and evaluate the effects of its prevention and control. [ Methods] Ecology research method was used to analyze epidemic characteristics of TB from 1990 to 2013 in Huangpu District. [Results] In 1990-2013, the average incidence rate of TB was 37.37/105, showing a trend of gradual decline as a whole and the average death rate was 0.47/105 .The incidence rate in elderly males aged over 65 was the highest.Those with the highest morbidity were accordingly retirees, workers, housekeeping and the unemployed. [ Conclusion] The overall effect of control of TB was obvious in Huangpu District from 1990 to 2013.While public's lack of knowledge and awareness, non-standard cure, high rate of drug resistance and large numbers of floating population posed challenge for prevention and control.TB cure and control still need to be improved.
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<p><b>OBJECTIVE</b>To analyze the effects of cholesterol ester transfer protein (CETP) Taq1B polymorphism on the response of serum HDL-C to dietary factors in hyperlipidemia patients.</p><p><b>METHODS</b>All 141 hyperlipidemia residents in a community in Shanghai were investigated by a 3-day diet questionnaire. The serum lipids were analyzed, and the polymorphism of CETP gene was detected by PCR-RFLP method. The correlation between dietary factors and serum HDL-C in different genotype was analyzed when considering the effects of sex, age and body mass index.</p><p><b>RESULT</b>The HDL-C of hyperlipidemia patients was affected by dietary factors and CETP gene Taq1B polymorphism. The strength of the correlation between dietary factors and serum HDL-C was different among the genotype groups. The relation was shown closer in B(2)B(2) subjects than in B(1)B(1).</p><p><b>CONCLUSION</b>The Taq1B CETP gene polymorphism should be a strong determinant of HDL-C in hyperlipidemia patients, and might contribute to the heterogeneity in HDL-C response to dietary intervention.</p>