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1.
An. bras. dermatol ; 93(1): 111-113, Jan.-Feb. 2018. tab, graf
Artigo em Inglês | LILACS | ID: biblio-887138

RESUMO

Abstract: Primary cutaneous amyloidosis is limited to the skin without involving any other tissue. Nodular amyloidosis is rare, and atrophic nodular cutaneous amyloidosis is even rarer. We describe the fourth case of atrophic nodular cutaneous amyloidosis by searching PubMed databases. A 52-year-old female presented to our hospital with a 2-year history of orange papules and nodules without subjective symptom on her right abdomen. Review of systems was negative. Atrophic nodular amyloidosis may progress to primary systemic disease in up to 7% of cases. Because our patient had no systemic involvement, she was diagnosed with atrophic nodular cutaneous amyloidosis based on characteristic symptoms and histopathologic examination. Routine follow-up for this patient is necessary to detect any potential disease progression.


Assuntos
Humanos , Feminino , Pessoa de Meia-Idade , Dermatopatias/patologia , Amiloidose/patologia , Atrofia/patologia , Dermatopatias/diagnóstico , Parede Abdominal/patologia , Amiloidose/diagnóstico
2.
Indian J Dermatol Venereol Leprol ; 2015 Jan-Feb; 81(1): 43-45
Artigo em Inglês | IMSEAR | ID: sea-154971

RESUMO

Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA‑B*5801 allele is a very strong marker for allopurinol‑induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol‑induced drug eruptions in patients carrying the HLA‑B*5801 allele and review the literature on the association between HLA‑B*5801 and allopurinol‑induced cADRs based on a MEDLINE and PubMed search.


Assuntos
Idoso , Alopurinol/efeitos adversos , Alopurinol/uso terapêutico , Toxidermias/etiologia , Toxidermias/genética , Antígenos HLA-B/classificação , Antígenos HLA-B/genética , Masculino , Pessoa de Meia-Idade , MEDLINE , PubMed
3.
An. bras. dermatol ; 88(6,supl.1): 11-14, Nov-Dec/2013. graf
Artigo em Inglês | LILACS | ID: lil-696785

RESUMO

We present a case of PNP associated with Castleman's Disease. We have also reviewed the literature and described the characteristics of the two associated diseases. Gene clonal rearrangement was done to help diagnosis. We used, in addition, stereotactic radiosurgery which, as far as we know, has never before been employed to treat PNP associated with Castleman's Disease. This produced a good response, suggesting that it might be a good alternative treatment for PNP associated with Castleman's Disease when it is too difficult to operate.


Apresentamos um caso de PNP associada à doença de Castleman.Também revisamos a literatura, e referenciamos as características das duas doenças associadas. Um rearranjo genético clonal foi feito para ajudar o diagnóstico. Além disso, usamos a radiocirurgia que até então nunca havia sido utilizada para tratar PNP associada à doença de Castleman. Esta produziu uma boa resposta, sugerindo que pode ser uma boa alternativa para o tratamento de PNP associada com a doença de Castleman quando é muito difícil fazer uma cirugia convencional.


Assuntos
Humanos , Masculino , Pessoa de Meia-Idade , Hiperplasia do Linfonodo Gigante/complicações , Síndromes Paraneoplásicas/complicações , Pênfigo/complicações , Biópsia , Hiperplasia do Linfonodo Gigante/diagnóstico , Reação em Cadeia da Polimerase , Síndromes Paraneoplásicas/diagnóstico , Pênfigo/diagnóstico , Resultado do Tratamento
4.
Indian J Dermatol Venereol Leprol ; 2012 Mar-Apr; 78(2): 197-199
Artigo em Inglês | IMSEAR | ID: sea-141051
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