A comparative evaluation of visual, refractive, and patient-reported outcomes of three diffractive trifocal intraocular lenses

@#OBJECTIVE: To compare the visual, refractive, and patient-reported outcomes of eyes implanted with one of 3 trifocal intraocular lenses (IOLs). METHODS: This is a cross-sectional, comparative, non-interventional study wherein subjects implanted with FineVision Micro F, AT LISA tri 839MP or AcrySof IQ PanOptix trifocal IOL after phacoemulsification were recruited. Manifest refraction, uncorrected and corrected visual acuity (VA) at distance, intermediate and near vision, contrast sensitivity, modulated transfer function (MTF) values and questionnaire answers were compared among the 3 groups using analysis of variance (ANOVA). RESULTS: Fifty-seven (57) eyes were included in the study: 21 eyes with FineVision (group A), 21 eyes with LISA tri (group B), and 15 eyes with PanOptix IOL (group C). The post-operative mean manifest spherical equivalent was -0.01D, -0.07D, and 0.05D, respectively (p=0.083). Uncorrected distance VA and best-corrected distance VA were similar among the groups. Groups A and C had better uncorrected and corrected intermediate VA at 80 cm and at 60 cm compared to group B. Group A had significantly better uncorrected near visual acuity than groups B and C (p=0.032). Mesopic contrast sensitivity testing showed group C had higher contrast sensitivities without glare in at the spatial frequency of 6 CPD (p=0.038) and with glare at 3 CPD (p=0.039) and at 12 CPD (p=0.009). MTF average height analysis showed that the group A had significantly superior resolution in far targets compared to groups B and C (p=0.001). At near targets, groups A and C had better resolutions compared to group B (p=0.017). There was no significant difference in patient satisfaction for far, intermediate and near VA among the groups. CONCLUSION: Eyes implanted with any of the 3 trifocal IOL designs achieved excellent uncorrected and bestcorrected distance, intermediate and near vision. FineVision and PanOptix provided significantly better intermediate vision than LISA tri at both 80 cm and 60 cm testing distance. FineVision had better near visual outcomes than PanOptix and LISA tri. Patient satisfaction was high in all 3 trifocal IOLS

Clinical observation of multifocal intraocular lens with aspheric astigmatism in cataract surgery / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: By comparing the aspheric and multifocal Toric intraocular lens and the aspheric intraocular lens in cataract patients,to observe the patients` visual quality,to evaluate the patients` distance visual acuity,near visual acuity,Pseudo-accommodative power,residual astigmatism,the rotational stability of AcrySof IQ Toric Restor intraocular lens (IOLs),contrast the rate of off-distance glass,the rate of off-near glass and patient satisfaction after the implantation of AcrySof IQ Toric Restor IOL in the cataract patients with preexisting corneal astigmatism.METHODS:Carried out in 46 patients (48 eyes) with age-rated cataract who receiving phacoemulsification and implantation of artificial lens in our department during February 2014 to June 2016.All the cases were randomly divided into 2 groups: experimental group: 23 cases (24 eyes),AcrySof IQ ReSTOR Toric IOL was implanted after phacoemulsification;control group: 23 cases (24 eyes),AcrySof IQ was implanted.Uncorrected distance visual acuity (UCDVA) and best corrected distance visual acuity (BCDVA),uncorrected near visual acuity (UCNVA) and best-corrected near visual acuity(BCNVA),Pseudo-accommodative power,residual astigmatism,preoperative and postoperative corneal astigmatism,the rate of off-distance glass,the rate of off-near glass and patient satisfaction were measured at 6mo postoperatively follow-up.RESULTS: BCDVA and BCNVA were not statistically different between the two groups(P<0.05).At 1wk,1,3 and 6mo postoperatively of UCDVA the experimental group were statistically better than the control group (P<0.05).UCNVA were also statistically better than the control group (P<0.05).The mean residual astigmatisms 1wk,1,3 and 6mo postoperatively were statistically differences between the control group and experimental group (P<0.05).At 6mo postoperatively,patients satisfaction of experimental group were significantly better than control group (P<0.05).Spectacles independence for near vision achieved 83% and 17% in experimental group and control group,experimental group were statistically better than control group(P<0.05).Spectacles independence for distance vision achieved 92% and 67% in experimental group and control group,experimental group were statistically better than control group(P<0.05).CONCLUSION:The results indicate that AcrySof IQ ReSTOR Toric IOLs may provide a better uncorrected distance visual acuity and uncorrected near visual acuity,which can significantly reduce preexisting corneal astigmatism in cataract surgery,improve spectacles independence for distance vision and spectacles independence for near vision,have a high patient satisfaction.

Early clinical effects of phacoemulsification cataract surgery with implantation of Acrysof IQ Restor multi-focal toric lens / 医学研究生学报

Objective Acrysof IQ Restor multifocal toric intraocular lens ( IOL) is a new product , which allows a single sur-gical procedure for presbyopia correction and corneal astigmatism management .This study was to evaluate the early clinical effects of phacoemulsification cataract surgery with implantation of a diffractive multifocal toric IOL . Methods We retrospectively analyzed 7 cases (9 eyes) of corneal astigmatism ≥1.0 diopter (D) treated by phacoemulsification with implantation of an Acrysof IQ Restor toric IOL.The patients were followed up for 3 months for observation of uncorrected distance visual acuity ( UDVA) , best corrected distance visual acuity ( CDVA) , uncorrected near visual acuity ( UNVA ) , best corrected near visual acuity ( CNVA ) , spherical equivalent (SE) refraction, focal depth, residual astigmatism, rotational stability of the IOL, contrast sensitivity (CS), and spectacle independ-ence preoperatively and at 1 week, 1 month, and 3 months after operation . Results At 3 months after surgery , the UDVA ( log-MAR), CDVA, UNVA, and CNVA were 0.07 ±0.10, 0.02 ±0.11, 0.12 ±0.06, and 0.08 ±0.07, respectively, with an SE re-fraction within ±0.50 D of the attempted spherical correction in 8 eyes (88.9%) and a focal depth of (5.32 ±1.78) D.The residual astigmatism at 3 months was significantly reduced as compared with the baseline ([0.25 ±0.28] vs [1.55 ±0.39] D, P0.05).At 3 months, the mean IOL axis rotation was (3.11 ±1.61)°and CS was remarkably im-proved ( P0.05) except at 18.0 cpd (P<0.05). Conclusion Implantation of the Acrysof IQ Restor multifocal toric IOL provides excellent overall quality of vision, spectacle independence, visual quality, and rotational stability for patients with cataract and corneal astigmatism.

Comparison of Visual Function Between Two Aspheric Intraocular Lenses After Microcoaxial Cataract Surgery

PURPOSE: To compare the visual function and postoperative refraction between two aspheric intraocular lenses (IOLs) after microcoaxial cataract surgery. METHODS: A prospective analysis of 60 eyes of 58 patients who had undergone microcoaxial phacoemulsification and implantation of aspheric IOLs (AcrySof IQ, 30 eyes; Akreos MI60, 30 eyes) was performed. The best corrected visual acuity (BCVA), spherical equivalent, intraocular pressure (IOP), corneal thickness, endothelial cell density (ECD), predictability of postoperative spherical equivalent, higher order aberrations, contrast sensitivity test, satisfaction, and glare were evaluated during the follow-up period of three months. RESULTS: There were no significant differences in BCVA, spherical equivalent, IOP, corneal thickness, or ECD (p>0.05). The predictability of the postoperative spherical equivalent in the AcrySof IQ and Akreos MI60 IOL groups was not significantly different (p=0.59), and the two groups showed good anterior-posterior stability during the postoperative three months. There were no significant differences in higher order aberrations, contrast sensitivity test, satisfaction or glare (p>0.05). CONCLUSIONS: Both AcrySof IQ and Akreos MI60 implantation groups showed similar visual functions and postoperative spherical equivalents after microcoaxial cataract surgery.

Ocular Aberrations and Contrast Sensitivity in Eyes Implanted with Aspheric and Spherical Intraocular Lenses

PURPOSE: To compare spherical aberration, higher-order aberration, and contrast sensitivity of eyes implanted with aspheric (AcrySof IQ) or spherical (AcrySof Natural) intraocular lenses. METHOD: Seventy-five eyes implanted with posterior chamber intraocular lenses were divided into two groups: AcrySof IQ (35 eyes) and AcrySof Natural (40 eyes). Wavefront analysis (spherical, higher-order and total aberration) using iTace, and contrast sensitivity (under photopic and mesopic condition) using Optec 6500 were performed at 1 month and 3 months postoperatively. RESULT: One month after surgery, the IQ IOL (intraocular lens) group had lower values of spherical aberration (p<0.001) and higher-order aberration (p=0.048) than the Natural IOL group. The IQ IOL group also showed better contrast sensitivities at 1.5- and 3-cpd spatial frequencies in mesopic conditions. Three months after surgery, the IQ IOL group had less spherical aberration (p<0.001) and higher-order aberration (p=0.027) than the Natural IOL group and showed better contrast sensitivities at the 3-cpd spatial frequency in mesopic conditions. CONCLUSIONS: Aspheric AcrySof IQ IOL induced significantly less higher-order aberration and spherical aberration than AcrySof Natural IOL. The contrast sensitivity was better under mesopic conditions in the AcrySof IQ IOL-implanted group.