RESUMO
El antígeno específico de próstata (PSA, del inglés, Prostate Specific Antigen) es una glicoproteína producida por la próstata, y es el marcador tumoral de mayor uso. Sin embargo, su baja especificidad para diferenciar entre cáncer de próstata y otras alteraciones no malignas, como la hipertrofia benigna de la próstata (HBP) y la prostatitis aguda, limitan su utilidad diagnóstica
Prostate Specific Antigen (PSA) is a glycoprotein produced by the prostate and is the most widely used tumor marker. However, its low specificity to differentiate between prostate cancer and other non-malignant conditions, such as benign prostate hypertrophy (BPH) and acute prostatitis, limits its diagnostic utility
Assuntos
Antígeno Prostático Específico , Hiperplasia Prostática , Prostatite , Glicoproteínas da Membrana de Plaquetas , Biomarcadores TumoraisRESUMO
We present an unfrequent case of acute diverticulitis mimmicking acute prostatitis. Case report: A 72-year-old man suffering from hypogastric and genital pain, fever and dysuria, with an edematous and tender prostate at physical examination, was initially diagnosed of acute prostatitis. 24 hours later the patient developed left lower quadrant pain and abdominal distension. A CT scan was performed, showing pneumoperitoneum and acute sigmoid diverticulitis signs. The patient underwent a Hartmann's procedure.
Presentamos un caso infrecuente de diverticulitis aguda con manifestaciones clínicas sugerentes de prostatitis aguda. Caso clínico: Varón de 72 años, presenta dolor hipogástrico y en región genital, fiebre y disuria, palpándose una próstata edematosa y dolorosa al tacto rectal, por lo que es inicialmente diagnosticado de prostatitis aguda. A las 24 horas el paciente desarrolla un cuadro de distensión abdominal y dolor en fosa ilíaca izquierda. Una TC abdominal mostró neumoperitoneo y signos de diverticulitis aguda. Se intervino al paciente realizando una intervención de Hartmann.
Assuntos
Humanos , Masculino , Idoso , Diverticulite/cirurgia , Diverticulite/complicações , Diverticulite/diagnóstico , Prostatite/etiologia , Doença Aguda , Doenças Urológicas/etiologia , Perfuração IntestinalRESUMO
PURPOSE: We would like to know whether the serum PSA could be used as a biochemical marker in the diagnosis and follow-up of patients with acute prostatitis. MATERIALS AND METHODS: The records of 23 patients with acute prostatitis whose serum PSA levels were checked, from February 1995 to February 2001, were reviewed retrospectively. Mean patient age was 54.2 years (range 27-80). We followed serum PSA of the patients regularly with 1-2 weeks interval for one month and after then with 2-4 weeks interval. RESULTS: The elevation of serum PSA level above 4ng/ml was found in 22/23 (95.6%) patients with acute prostatitis. Mean initial PSA level was 26.6ng/ml (range 1.5-100). Out of the 15 patients whose serum PSA levels were followed after treatment, 10 (66.7%) patients showed normalization of PSA level within 6 weeks. In 3 of 15 (20%) patients, PSA level was normalized after 6 weeks. Two patients whose PSA levels were elevated after resolution of prostatitis underwent transrectal ultrasonography of the prostate with biopsies. None was found to have adenocarcinoma of prostate. CONCLUSIONS: In the majority of patients with acute prostatitis, serum PSA levels were elevated initially and declined after appropriate treatments. Therefore, serum PSA level could be used as a biochemical marker in the diagnosis and follow-up of patients with acute prostatitis as an adjunct to the clinical findings.