RESUMO
Objetivo: describir los factores de riesgo presentes en un grupo de pacientes con lesiones intraepiteliales escamosas (LIE) de cérvix en una entidad de referencia para mujeres del régimen subsidiado en la ciudad de Cartagena entre los años 2007 y 2012. Materiales y métodos: estudio descriptivo. La población de estudio la conformaron pacientes con diagnóstico histológico de lesiones intraepiteliales escamosas, que asistieron a la Unidad de Patología Cervical y Colposcopia de la Clínica Maternidad Rafael Calvo, de Cartagena (Colombia). La muestra fueron 150 mujeres mayores de 18 años. Resultados: el promedio de edad fue 35,5 años, el62% del grupo estudio se encontró entre los 20 y 39 años. El 78% presentó LIE debajo grado y el 22% LIE de alto grado. El 74% tuvo dos o más embarazos, 44,1% su primer embarazo fue antes de los 20 años, 64% tuvieron dos o más partos, 94.66% de la población no era fumadora, 4% refirió consumir alcohol regularmente, 54% afirmó haber tenido dos o más compañeros sexuales, 62% inició su vida sexual entrelos 16-20 años, 22% usa anticonceptivos hormonales y 38% no utiliza métodos de planificación familiar. Conclusiones: la multiparidad, la cantidad de embarazos, la sexarquia temprana, el múltiple número de parejas sexuales y los métodos hormonalesde anticoncepción, fueron los factores de riesgo con mayor frecuencia encontrados en las pacientes con lesiones intraepiteliales escamosas del cerviz en Cartagena.
Introduction: the squamous intraepithelial lesions are an indispensable condition for the occurrence of cervical cancer, one of the leading causes of death from gynecological cancer. The aim of this study is to show the risk factors more frequently found inpatients with squamous intraepithelial lesions of the cervix in this population. Materials and methods: a descriptive study of patients with squamous intraepithelial lesions, who attended the unit of cervical pathology and colposcopy in Clínica Maternidad RafaelCalvo. Results: the average age was 35.5 years, 62% of the study group was between20 and 39 years. 78% had LSIL and 22% HSIL. 74% had two or more pregnancies,44,1% had their first pregnancy before age 20, 64% had two or more deliveries, 62%the age of first intercourse was between 16-20 years, 54% had two or more sexual partners, 22% use hormonal contraceptives. 94.66% of the population didnt smokeand 78.66% deny alcohol. Conclusions: multiparity, early onset of sexual intercourse, multiple sexual partners and use hormonal contraceptives were the factors most frequently found in the population of patients with squamous intraepithelial lesions of the cervix in Cartagena.
Assuntos
Colo do Útero , Fatores de Risco , Neoplasias do Colo do ÚteroRESUMO
We have designed a five-year multicentre prospective cohort study in women who are both human papillomavirus (HPV)-positive with either atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL) of cervix. This study aimed to analyze the risk of developing a high-grade squamous intraepithelial lesion (HSIL) from either ASCUS or LSIL in HPV-positive women, so called 'progression' rate, to investigate differences in the progression rates according to HPV type-specific infection, and to evaluate the various factors associated with the persistence or clearance of HPV infection in the Korean population. At present, the study protocol composed of cervical cytology, HPV DNA testing, and questionnaire have been conducted actively since the first participant was enrolled in 2010. This study is the first nationwide Korea HPV cohort study. Our data will provide valuable information about not only the ambiguous cytology results of ASCUS and LSIL but also the effect of the specific HPV type and other various factors on the progression to HSIL. Finally, the results of our study will be helpful and applicable to determine the primary cervical cancer prevention strategies.