RESUMO
Objective: To study the chemical constituents from the roots of Lycium chinense. Methods: The compounds were isolated and purified by silica gel, ODS and Sephadex LH-20 chromatography in addition to preparative-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analysis. Results: Twelve compounds were isolated from the EtOAc fraction of the root of Lycium chinense and identified as grossamide K (1), grossamide (2), dihydrogrossamide (3), cannabisin H (4), 1,2-dihydro-6,8-dimethoxy-7-hydroxy-1-(3,4-dihydroxyphenyl)-N1,N2-bis [2-(4-hydroxyphenyl)ethyl]-2,3-naphthalene dicarboxamide (5), cannabisin D (6), (1,2-trans)-N3-(4-acetamidobutyl)-1-(3,4-dihydroxyphenyl)-7-hydroxy-N2-(4-hydroxyphenethyl)-6,8-dimethoxy- 1,2-dihydronaphthalene-2,3-dicarboxamide (7), cannabisin F (8), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxyphenethyl)amino]-3-oxopropyl} phenyl)-3-(4-hydroxy-3-methoxyphenyl)-N-(4-acetamidobutyl)acrylamide (9), (E)-2-(4,5-dihydroxy-2-{3-[(4-hydroxylphenethyl) amino]-3-oxopropyl}phenyl)-3-(4-hydroxy-3,5-dimethoxyphenyl)-N-(4-hydroxyphenethyl)acrylamide (10), (+)-lyoniresinol-3α-O-β-D- glucopyranoside (11), and (−)-lyoniresinol-3α-O-β-D-glucopyranoside (12). Conclusion: Compound 3 is a new natural product. Compounds 1, 2, and 4—8 are isolated from this plant for the first time.
RESUMO
Objective: To study the chemical constituents of Gastrodia elata. Methods: The constituents were isolated by various chromatographies, including preparative TLC, silica gel, Sephadex LH-20, and ODS columns, and their structures were elucidated on the basis of their physicochemical properties and spectral data. Results: Eleven compounds were isolated from 70% EtOH fraction eluted from resin column and their structures were identified as gastrodin (1), 4-hydroxybenzyl alcohol (2), 4-hydroxybenzoic acid (3), 4-hydroxybenzaldehyde (4), 4-hydroxybenz-yl methyl ether (5), parishin (6), 4-(methylsulfinylmethyl) phenol (7), dibutyl phthalate (8), dioctyl phthalate (9), 4, 4'-dihydroxydiphenyl methane (10), and grossamide (11). Conclusion: Compound 7 is a new natural product, and compounds 9 and 11 are isolated from the plants of Orchidacee for the first time.
RESUMO
OBJECTIVE: To study the chemical constituents of Alocasia macrorrhiza (L.) Schott. METHODS: Chemical constituents were extracted by organic solvents, isolated and purified by chromatographic techniques with silica gel, polyamide, ODS, Sephadex LH-20, semi-preparative HPLC and recrystallization. Their structures were identified on the basis of physicochemical properties and spectral data analyses of MS and NMR, et al. RESULTS: Nine compounds were isolated from its rhizoma and identified as glycosmisic acid (1), N-trans-feruloyltyramine(2), grossamide(3), protocatechuic acid(4), borneol acetate(5), vanillic acid(6), methyl 4-hydroxybenzoate(7), β-daucosterol(8), and β-sitosterol(9). CONCLUSION: Compounds 1-9 were isolated from Alocasia macrorrhiza for the first time.