RESUMO
Objective: To study the chemical constituents from the ethyl acetate extract of the leaves of Adinandra nitida. Methods: Several column chromatography including silica gel, Sephadex LH-20 gel, and ODS were applied in isolation and purification. The structures were elucidated on the basis of physicochemical properties and spectral data from 1H-NMR, 13C-NMR, ESI-MS and so on. Results: Nine flavonoids, three phenolic acids, and two other compounds were isolated and determined as apigenin (1), naringenin (2), luteolin (3), chrysoeriol (4), (-)-epicatechin (5), quercetin (6), quercitrin (7), camellianin A (8), camellianin B (9), p-methoxyphenol (10), protocatechuic acid (11), 3,3',4,4'-tetrahydroxybiphenyl (12), scopoletin (13), and palmitic acid (14). Conclusion: Compounds 3, 10-14 are firstly isolated from the plant of A. nitida and compounds 3, 10, 12, and 13 are obtained from Theaceae for the first time.
RESUMO
Objective: To study the chemical constituents from the leaves of Adinandra nitida. Methods: The chemical constituents of the plant were isolated and purified by column chromatography and their structures were elucidated on the basis of physicochemical properties and spectral data. Results: Eleven triterpenoids, two diterpenoids, and two steroids were obtained and determined to be ursolic acid (1), 18-hydroxyursolic acid (2), 2α,3α-dihydroxyursolic acid (3), 3α,19α-dihydroxyursolic acid (4), euscaphic acid (5), 3β,19α,23-trihydroxyursolic acid (6), 2α,3α-dihydroxyursolic acid-28-O-β-D-glucopyranoside (7), kajiichigaside F1 (8), oleanolic acid (9), arjunetin (10), betulinic acid (11), cassipourol (12), α-tocopherol (13), daucosterol (14), and β-sitosterol (15). Conclusion: Compounds 1-4, 6, 7, 9, and 11-13 are obtained from the leaves of A. nitida for the first time.