Efficacy of Pixel 2 940 nm erbium laser combined with VB12 in treatment of acne pitting scar / 中华医学美学美容杂志

Objective:To investigate the efficacy of pixel 2 940 nm erbium laser combined with vitamin B12 in the treatment of acne sunken scar.Methods:From July 2017 to June 2019, 96 patients with acne sunken scar were treated in the Department of Burn and Plastic Surgery of the Second People＇s Hospital of Jiaozuo City, Henan Province. They were randomly divided into two groups with 48 cases in each group. The control group was treated with routine therapy and the observation group was treated with pixel 2 940 nm erbium laser combined with vitamin B12. The therapeutic effects, acne scar weight score (ECCA), skin condition and adverse reactions were compared between the two groups.Results:The total effective rate of the control group was 77.08% (37/48), which was lower than that of the observation group 91.67% (44/48) ( P<0.05); The incidence of adverse reactions, pore and amethyst in ECCA score of the control group were (18.14±9.33), 18.75% (9/48), (32.25±8.41) and (18.24±5.12), which were higher than those of the observation group (26.45±12.60), 4.17% (2/48), (28.24±7.52) and (15.63±4.34) ( P<0.05), respectively. Conclusions:Pixel 2 940 nm erbium laser combined with vitamin B12 is effective in the treatment of acne sunken scar, with less adverse reactions and high safety. It is worthy of clinical application.

The research progress on artemisinin resistance and mechanism of spleen clearing Plasmodium / 中国药理学通报

The resistance to artemisinin generated by plasmodium is defined as follows: After being treated with ACTs for three days, the time to clear plasmodium from the blood of patients with malaria becomes prolonged. The elimination rate of plasmodium in vivo is not only related to the parasiticidal efficacy of antimalarial drugs, but also affected by biological factors such as the mutation of plasmodium themselves, the regulation of human immune function(such as the recognition and processing of phagocytes) , and the efflux of foreign l>odies from immune organs. This article primarily reviews the mutation of plasmodium themselves , the physical and biochemical process of the spleen eliminating plasmodium, including K13 changes, the two blood circulation pathways of the spleen. Since the endothelial cell gap of the splenic venous sinus is elastic, plasmodium or red blood cell debris can be trapped by physical and mechanical sensing methods. The red pulp is the main venue to filter blood, where the immune cells are responsible for the removal of the residues of plasmodium. The physical process of the splenic venous sinus trapping plasmodium is called pitting, and its incidence is influenced by the growth cycle of plasmodium and therapeutic drugs. In this paper, the function of the spleen to eliminate plasmodium will be explained, in an attempt to provide a reference for the biological nature of the artemisinin resistance generated by plasmo-dium.

Remitting Seronegative Symmetrical Synovitis with Pitting Edema associated with Lung Malignancy:Case Report and Literature Review / 中国医学科学院学报

Remitting seronegative symmetrical synovitis with pitting edema(RS3PE),the inflammatory arthritis attacking mainly elderly males,is characterized by symmetrical synovitis with pitting edema of the dorsum of hands and feet and the absence of rheumatoid factor.RS3PE commonly accompanies malignant tumor,infections and other diseases.Here we report a case of RS3PE associated with lung malignancy and review other six cases to summarize the clinical features,treatment and prognosis.

Serological and Molecular Detection of Latent Viruses in the Apple Germplasm Bank of Santa Catarina

Abstract The Apple Germplasm Bank (AGB) of Santa Catarina Agricultural Research and Rural Extension Company - Epagri, AGB-Epagri, is the largest of the genus Malus in Brazil. Twenty-eight main accessions of this bank were virus screened through DAS-ELISA, RT-PCR and IC-RT-PCR during two consecutive reproductive cycles, and each accession showed latent mixed infection by at least two species, among ASGV, ASPV and ACLSV. The combined use of diagnostic methods helped overcome inconsistencies commonly found in apple virus detection and was shown essential for the AGB-Epagri can be safely used as a source of genetic variability and for the exchange of virus-free propagative material.

Picaduras por aracnomorfos en la ciudad de Sucre (Chuquisaca, Bolivia) / Arachnomorph´s pitting in the city of Sucre (Chuquisaca, Bolivia)

Se realizó un estudio de picaduras de aracnomrofos en la ciudad de Sucre (Chuquisaca). El método comprendió el uso de encuestas semiestructuradas, donde se consultó sobre la percepción que tienen, sintomatologías y conocimiento local sobre métodos de curación. Los resultados obtenidos evidencian que la mayoría tiene fobia hacia los arácnidos. El conocimiento local, permite conocer los diferentes tipos de arañas y escorpiones que residen en los domicilios. Se describe los síntomas que causan debido al efecto de las picadas, además de los métodos convencionales y naturales de curación.

We study of pitting Arachnomorph´s was held in the city of Sucre (Chuquisaca). The method realized using semistructured interviews, which were consulted on the perception, symptom and local knowledge of healing methods. The results show that most have phobia of arachnids. Local knowledge, allows to know the different types of spiders and scorpions that live in the homes. They are causing symptoms due to the effect of bites and of natural and using the conventional and natural healing methods.

Remitting Seronegative Symmetrical Synovitis with Pitting Edema Syndrome: A Case Report

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome is a rare condition that occurs in elderly individuals. It is characterized by sudden onset of bilateral symmetrical distal tenosynovitis that accompanied by obvious swelling of the hand with pitting edema and absence of rheumatoid factor (RF). This disease entity sometimes presented as overlap syndrome with other rheumatic diseases and needed to be differentiated from those. However, if the diagnosis is confirmed, the response to steroid is good. The purpose of this report is to describe the case of RS3PE syndrome presented with bilateral hand dorsum edema in a middle-aged woman.

Solid Facial Edema Refractroy to Various Treatment / 대한피부과학회지

No abstract available.

Corrosion of orthodontic brackets in different spices:In vitro study.

Context: Moist environment in the mouth varies and causes variable amounts of corrosion of dental materials. This is of concern particularly when metallic implants, metallic fillings, orthodontic appliances are placed in the hostile electrolytic environment in the human mouth. Components of diet rich in salt and spices are important factors influencing the corrosion of metallic appliances placed in the oral cavity. Aims: To study in vitro corrosion of orthodontic metallic brackets immersed in solutions of salt and spices in artificial saliva. Materials and Methods: Orthodontic brackets were used for corrosion studies in artificial saliva, salt, and spices using electrochemical technique and surface analysis. Electrochemical studies using different parameters were done in solutions of artificial saliva containing salt and spices. Photomicrographs from the optical microscope were also obtained. Results: Results of corrosion studies have clearly demonstrated that certain spices such as turmeric and coriander are effective in reducing corrosion, whereas salt and red chili have been found to enhance it. Surface analysis of small pits present on the surface of the as-received bracket will initiate corrosion which leads to more pitting.

A Case of Eosinophilic Fasciitis Presenting as Pitting Edema of the Lower Extremities

Eosinophilic fasciitis is a rare disease characterized by diffuse fasciitis with peripheral eosinophilia and progressive induration and thickening of the skin and soft tissues. We report a 19-year-old female who presented with pitting edema in both lower extremities. She had a history of excessive physical activity before her symptoms developed. Physical examination revealed 2+ pitting edema in both lower legs. She complained of mild pain in both knee joints and feet, with no tenderness or heating sensations. Laboratory results were unremarkable except for severe eosinophilia. Parasite infection, venous thrombosis, and cardiac and renal problems were excluded. A magnetic resonance imaging study of both lower extremities revealed increased signal intensity in the subcutaneous lesions, consistent with superficial inflammation of the fascia. Mixed perivenular lymphoplasmacytic and eosinophilic infiltration in the subcutaneous lesion were observed on biopsy. The patient was treated with corticosteroids, resulting in remarkable improvement in both edema and eosinophilia.

Corrosion behavior of titanium wires: An in vitro study.

Context: Teeth and restorations are subjected continuously to degradation in hostile physical and chemical environments, resulting in corrosion. Component of liquid or solid is an important factor influencing the corrosion of metallic appliances placed in the oral cavity. Aims: To study in vitro corrosion of titanium wires immersed in solutions of toothpaste and chocolate in artificial saliva. Materials and Methods: Immersion test and electrochemical studies using different parameters, including corrosion potential (E corr ), cathodic Tafel constant (βc), anodic Tafel constant (βa), corrosion current (I corr ), polarization resistance (R p ), and corrosion rate of titanium wires, were done in solutions of artificial saliva containing Colgate™ toothpaste and Amul™ chocolate. Photomicrographs were also taken. Results: The results showed degradation of titanium wires by electrochemical attack when they were placed in the hostile electrolytic environments provided in the experiments. Surface analysis of titanium wires showed pitting and localized attacks on the surface. Pitting corrosion was found in the titanium wires.

Remitting seronegative symmetrical synovitis with pitting edema syndrome: a clinical and outcome analysis of 14 cases and review of literature / 中华风湿病学杂志

Objective To analyze the clinical features and outcome of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome,and enhance the understanding of it.Methods Fourteen cases of RS3PE syndrome treated in the Department of Rheumatology and Immunology were analyzed retrospec-tively,including the clinical characteristics,laboratory data.Data were presented as -x±s.Results Fourteen patients(nine man,five women) with RS3PE were enrolled.Their age was (68±9) (range:52-78)years.The main clinical features were acute onset symmetrical edema in both hands and feet and polyarthritis.Polyarthritis were involved in hand joints in 14 patients,wrists in 13 patients,knees in 10 patients,ankles in 9 patients,and shoulders in 8.In laboratory examinations,the average value of erythrocyte sedimentation rate was (68±26) mm/l h and C-reactive protein was (49±41) mg/L.Mild anemia of normocytic-normochromic type and mild low level of serum albumin were frequent findings.Antinuclear antibody was present only in one patient at low titer (1∶20).Rheumatoid factor and other auto antibodies were all negative in patients.Before corticosteroid treatment,the MRI test was performed in 8 patients and revealed prominent synovitis and articular effusion.Two cases had bone erosions on MRI; five patients were fuond to have malignant tumors,three of them initially presented with RS3PE.Polyarthritis and edema were relieved after treated with low dose corticosteroids and DMARDs drugs.But those patients with cancer were easily to recurr.Conclusion RS3PE syndrome is relatively uncommon.It occurs predominantly in elderly men and is characterized by rapid-onset symmetrical polyarthritis,presence of pitting edema of both hands and feet.Erosive changes can be seen on MRI.Patients usually have dramatic response to low dose corticosteroids and DMARDs drugs.Patients should be closely followed as RS3PE is closely related to cancer.

Effects of Seifu on Blood Pressure, Pain and Edema / 日本温泉気候物理医学会雑誌

<B>Introduction</B><BR>  Seifu, devised in 1992 by Xu, is a method of treatment through “pulling the skin”, unlike the approaches of treatment adopted in Shiatsu, massage, or acupuncture. This paper reports our recent evaluations of the effects of Seifu on the blood pressure, pain, and edema.<BR><B>Materials and Methods</B><BR>  The blood pressure was measured before and after Seifu in 36 individuals (mean age : 78.6±6.6 years) who underwent Seifu for 5 sessions or more. The effects on edema were evaluated in 14 individuals aged 45-90. Changes in the severity of edema following Seifu were analyzed. The effects on pain were evaluated in two ways.<BR>1) Effects on acute pain<BR>  The effects on pain arising from injection into the knee were evaluated in three groups of patients with osteoarthritis of the knee: Group A (injection after the application of Seifu to the acupuncture point Gohkoku (LI4); n=7, mean age: 72.8±2.8 years), Group B (injection after the application of Seifu to the area around the knee; n=198, mean age: 75.3±9.1 years) and Group C (injection after the application of Seifu to the acupuncture point Saninkoh (SP6) ; n=62, mean age: 75.0±7.5 years).<BR>2) Effects on subcuate and chronic pain<BR>  Pain was evaluated before and after Seifu using a visual analog scale (VAS) in 103 patients with some subacute or chronic pain(n=594, mean age: 73.4±12.4 years).<BR><B>Results</B><BR>1. Blood pressure<BR>  The blood pressure decreased significantly in 5 and increased significantly in the normal range in 1 of the 36 subjects. No significant change in the blood pressure was noted in the other 30 subjects.<BR>2. Edema<BR>  Seifu was effective against pitting edema. However, in pateints followed for long periods of time after the surgical treatment of breast cancer, the skin hardness decreased but edema showed no marked reduction. Seifu exerted no effect on Quincke edema.<BR>3. Pain<BR>1) Acute pain<BR>  Pain at the time of injection was not alleviated in Group A. Pain at the time of injection was alleviated in 73.3% of the subjects from Group B and 69.4% from Group C. This percenatge did not differ significantly between Groups B and C.<BR>2) Subacute and chronic pain<BR>  Mean VAS±SD decreased significantly from 6.6±2.0 before to 3.4±1.8 after Seifu (p<0.001).<BR><B>Discussion</B><BR>  Seifu was shown to be effective against pitting edema. In cases where lymph ducts and vascular walls are intact, edema is expected to be alleviatedl by the Seifu-induced activation of lymph system autotransportation and its milking action on veins.<BR>Seifu seems to alleviate pain via the mechanism proposed in the gate control theory.<BR><B>Conclusion</B><BR>  Seifu is simple to apply and effective against pitting edema and pain, without exhibiting adverse effects on the blood pressure.

Nail Abnormalities in Alopecia Areata / 대한피부과학회지

BACKGROUND: Nail abnormalities may be associated with alopecia areata and nail abnormalities in alopecia areata are reported to range from 10%-66%. OBJECTIVES: This study investigates the clinical characteristics of nail abnormalities in alopecia areata, such as prevalence depending on sex, age and severities of hair loss. METHODS: Prospective analysis was undertaken by examining the finger nails of 424 alopecia areata patients and the nails of 465 non-alopecic patients were examined as controls. RESULTS: The number of the patients was 424(214 males, 210 females) and their mean age was 28.6 years (range 1-69). Nail abnormalities were noted in 98 (23.1%) out of 424 patients and in 24 (5.1%) out of 465 controls. According to age group, the prevalence of nail abnormalities was high at age under 9(31.7%) and at age of 10-19 (31.6%). The incidence according to severity of hair loss was 20.8% in below 50% of hair loss on scalp, 27.8% in 51%-100% of hair loss on scalp and 41.5% in 51%-100% of hair loss on the scalp and also involving body hair. The Frequent nail abnormalities were leukonychia punctata (8.5%) and pitting nail(8.0%). The other minor nail abnormalities were onychorrhexis, transverse ridging, trachyonychia, melanonychia, abnormality of lunula, onycholysis and koilonychia. CONCLUSIONS: The incidence of nail abnormalities in alopecia areata was significantly higher than in controls and the nail abnormalities were more common in children. The more severe was the degree of alopecia, the higher was the prevalence of nail abnormalities. Leukonychia punctata and pitting nail were frequently found in alopeica areata in Korea. The examination of nail in alopecia areata patients may be helpful in expectation of prognosis.

A Case of Remitting Seronegative Symmetrical Synovitis with Pitting Edema(RS3PE) Syndrome / 대한류마티스학회지

RS3PE is used to describe patients who have peripheral seronegative polyarthritis and pitting edema, especially in a man older than 60. It is characterized by sudden onset, high sedimentation rate, lack of bony erosion, remission within 18 months and good prognosis. Whether the RS3PE is a unique disease or syndrome has long been discussed, but conclusion was not obtained. We describe a 72 year old man of RS3PE with a review of the literature.

Pulmonary Diffusing Capacity in Patients with Liver Cirrhosis / 대한내과학회지

About a third of the patients with decompensated liver cirrhosis have reduced arterial oxygen saturation and are sometimes cyanosed in the absence of any apparent lung or heart disease; There is a reduction of diffusing capacity without a restrictive ventilatory defect. The aim of this study was to determine diffusing capacities in patients with chronic liver- diseases. The diffusing capacities and arterial oxygen saturations were measured in 25 patients with chronic active hepatitis(CAH), 9 early cirrhotics (early LC), 36 cirrhotics(Child's class A) and 11 cirrhotics(Child's class B). The anterior tibial area was observed for pitting edema, and Thallium-201 test per rectum(shunt index) was done. Hypoxemia was not observed in all subjects. The number of cases with decreased pulmonary diffusing capacity (DLco) is 3/25(12.0%) for CAH, 3/9(33.3%) for CAH with early liver cirrhosis(LC), 17/36(47.2%) for LC(Child's class A) and 6/11(54.5%) for LC(Child's class B). The mean+/-standard deviation of Dlco(% predicred) are 93.1+/-12.1 for CAH, 85.7+/-12.3 for CAH with early LC, 82.2+/-14.7 for LC(Child's class A) and 80.4+/-6.9 for LC(Child's class B), There is a significant difference between DLco in CAH and that in LC(Child's class A)(p0.3) had significantly lower DLco than these with lower shunt index(0.3) or pitting edema. This may be due to an increased systemic blood flow shunt and an increased generalized interstitial edema. Pulmonary function tests including diffusing capacity may be useful as prognostic parameters in patients with chronic liver disease, especially in those with CAH or early LC.