Chemical constituents from roots of Rosa cymosa / 中草药

To study the chemical constituents from the roots of Rosa cymosa. Methods: The chemical constituents were isolated and purified by silica gel chromatography repeatedly from the roots of R. cymosa, and their structures were identified by spectral analysis and chemical Methods:. Results: Sixteen compounds were isolated from the roots of R. cymosa and identified as 2-acetyl tormentic acid (1), 2-oxo-pomolic acid (2), 2α,3α,19α-trihydroxy-olean-12-en-28-O-β-D-glucopyranoside (3), kaji-ichigoside F1 (4), rosamultin (5), 23-hydroxy-tormentic acid (6), arjunetin (7), 2α,3α,19α,23-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (8), 1β, 3α,19α,23-tetrahydroxy-urs-12-en-28-O-β-D-glucopyranoside (9), catechin (10), 3,4-dihydroxyphenylethyl alcohol 8-O-β-D- glucoside (11), 3,4,5-trimethoxyphenyl-1-O-β-apiofuranosyl (1’’→6’)-β-glucoside (12), 4-hydroxy-3-methoxy-1-phenyl-O-(6’- O-galloyl)-β-D-glucopyranoside (13), ethyl gallate (14), 3,4,5-trimethoxyphenyl-β-D-glucopyranoside (15), and 3,4,5-trimethoxy- benzyl-β-D-glucopyranoside (16). Conclusion: Compounds 9, 11-13, 15, 16 were obtained from this genus for the first time, and compounds 3, 9, 11-16 were obtained from this plant for the first time.

Triterpenoids from roots of Rosa laevigata / 中草药

Objective: To study the triterpenoids from the roots of Rosa laevigata. Methods: The silica gel column chromatography was used to extract and separate the chemical constituents from the roots of R. laevigata. HPLC was used to analyze its purity, chemical and spectroscopy methods were used to determine their structures. Results: Thirteen constituents were isolated and identified as niga-ichigosides F2 (1), rosamultin (2), arjunetin (3), kaji-ichigoside F1 (4), auscaphic acid (5), cecropiacic acid 3-methyl ester (6), 2-acetyl tormentic acid (7), pomolic acid (8), 2α,3α-dihydroxyurs-12,18-dien-28-oic acid (9), 3β-E-feruloyl corosolic acid (10), fupenzic acid (11), 2-O-acetyl euscaphic acid (12), and 12,13-dihydromicromeric acid (13). Conclusion: Compounds 3, 6, 7 and 9-13 are obtained from this plant for the first time. Compounds 10, 12 and 13 are obtained from the plants of Rosa L. for the first time.