Influencing factors of mild cognitive impairment in people with subjective memory complaints / 第二军医大学学报

Objective To analyze the influencing factors of mild cognitive impairment (MCI) in the people with subjective memory complaints.Methods Convalescents aged over 60 years old with subjective memory complaints were enrolled in this study. Montreal cognitive assessment scale (MoCA), mini-mental state examination (MMSE) and activity of daily living scale (ADL) were used to screen the participants with MCI, who were allocated into the MCI group. Those without MCI were taken as controls. The sex, age, education backgrounds, chronic disease, physical activity, smoking, drinking and social activity were compared between two groups; and the prevalence rate of MCI and its influencing factors were analyzed. Results The prevalence rate of MCI was 71.15% (37/52) in the MCI group. The proportions of participants aged ≥70 years old, education period ≤12 years, with chronic disease, less physical activity and social activity were significantly higher in MCI group than those in the control group (P0.05). Conclusion Subjective memory complaint is closely related to MCI in the elderly. In those with subjective memory complaint, age, education background, presence of chronic disease, physical activity and social activity are the main influencing factors of MCI.

Analysis on the everyday memory characteristics and life quality of people with subjective memory complaints / 中华行为医学与脑科学杂志

Objective To investigate the characteristics of everyday memory of adults with subjective memory complaints (SMC),and probe into the correlation between everyday memory function and life quality.Methods Through convenience sampling,150 adults with SMC were face-to-face interviewed by an investigator,with demographic characteristics collected,and the cognition function,everyday memory function and life quality were also assessed during the interview.Results Among the 150 adults with SMC,the impairment rate of everyday memory function reached 96％,and the median score of RBMT-II was 16.00 (interquartile range 6.00),indicating a low level of everyday memory function,with the Name andDelayed recall Story items having lower scores.All participants were divided into two groups according to cognitive status,with 67 (44.70％) adults having normal cognitive function and 83 (55.30％) impaired cognitive function.After comparison,significant differences were found in the total score of RBMT-II and scores ofFaces recognition andDelayed recall Story between the two groups (P＜0.05).In all dimensions of SF-36,the median score of general health dimension for the 150 adults was 55.00 (inter-quartile range 31.25).The Spearman rank correlation analysis showed that the scores of several dimensions in RBMT-II were positively correlated with the scores of several dimensions in SF-36 (P＜0.05).Conclusion Everyday memory function of people with SMC was positively CorTelated with their life quality.

Association between Cerebral Amyloid Deposition and Clinical Factors Including Cognitive Function in Geriatric Depression: Pilot Study Using Amyloid Positron Emission Tomography

The purpose of this study was to explore the relationship between cerebral amyloid deposition and overall clinical factors including cognitive functions in geriatric depression by using 18F-florbetaben positron emission tomography. Thirteen subjects aged over 60 years who had a history of major depressive disorder and also had subjective memory complaint were included. Of all subjects, 3 subjects judged as amyloid positive, and the others judged as amyloid negative. Their memory, visuospatial functions and attention abilities were negatively correlated with amyloid deposition in specific brain regions, but their language and recognition abilities were not correlated with any region. The amyloid deposition of the whole brain region was significantly negatively correlated with immediate memory.

An analysis of cognitive status for elderly people with subjective memory complaint in seven community of Shapingba district in Chongqing city / 中华行为医学与脑科学杂志

Objective To explore the cognitive status of community-dwelling older adults with subjective memory complaints (SMC).Methods A total of 262 older adults with SMC were included based on convenience sampling.Face-to-face interview was conducted for demographic information collection and cognitive assessment.Statistical analyses Were undertaken using SPSS version 19.0.Results The participants with SMC had a low level of general cognitive function,with a mean score of 22.18±4.21 on the MoCA; the two cognitive domains of abstraction' and deIayed memory had the lowest scores,with an average score of 0.85±0.82 and 2.91± 1.50 respectively,and the average scoring rate lower than 60.00％.About 54.20％ of the older adults with SMC presented with cognitive impairment.The scores ofabstraction were low in the participants with and without cognitive impairment.In addition,the scores of visuospatial/executive function, language and delayed memory were low in the participants with cognitive impairment.The cognitive impairment of persons with SMC may be associated with age and marital status.The people over the age of 70 years and widowed ones are more likely to suffer from cognitive dysfunction.Conclusion The older adults with SMC have a low level of general cognitive function,and cognitive imPairment detection rate is higher.Advanced age and widowhood are important factors affecting their cognitive function.

Subjective memory complaint in the elderly may be related to factors other than cognitive deficit / Queixas subjetivas de memória no idoso podem ser relacionadas a outros fatores além de déficit cognitivo

Prevalence of subjective memory complaints (SMC) in elderly community dwellers (ECD) ranges from 25 to 50%. Some controversy exists over the association between SMC and cognitive status. Objective: We investigated whether a correlation in cognitive performance existed between two different groups according to SMC. Methods: The Mini Mental State Examination (MMSE) and Dementia Rating Scale-Mattis (DRS-Mattis) were applied to two groups: ECD (n=14) with SMC and residents (n=14) of a long-term care facility (LTCF) without SMC. Results: The median age in the ECD group was 81.0 years, and in the LTCF group was 75.0 years. There was a statistically significant difference (p=0.048) between these groups regarding age. Concerning schooling (1-8 or ?9 years), there was no statistically significant difference between the groups (p=0.638). No statistically significant difference between the two groups was found for scores on the cognitive tests. Conclusion: SMC might be related to extrinsic factors other than insipient cognitive decline.

A prevalência de queixa subjetiva de memória (QSM) em idosos da comunidade (IRC) varia de 25-50%. Controvérsias existem a respeito da associação entre QSM e cognição. Objetivos: Foi investigado se há correlação entre QSM e declínio cognitivo em dois diferentes grupos. Método: Foi aplicado o Mini Exame do Estado Mental (MEEM) e a Escala de Avaliação de Demência Mattis (DRS-Mattis) em dois grupos de idosos: IRC (n=14) que apresentaram QSM e residentes (n=14) de uma instituição de longa permanência (ILP) sem QSM. Resultados: A mediana de idade do grupo ?IRC? foi de 81,0 anos e a do grupo ?ILP? foi de 75,0. Houve diferença estatisticamente significante (p=0,048) entre eles, considerando a idade. Não houve esta diferença (p=0,638) na distribuição dos indivíduos quando analisada a escolaridade (1-8 ou ?9 anos). Considerando-se os escores dos instrumentos cognitivos, não houve diferença estatisticamente significante entre grupos. Conclusões: QSM pode estar relacionada a outros fatores em idosos, e não somente à presença de declínio cognitivo.