RESUMO
Objective:To investigate the correlation between overall recurrence rate,survival rate,and the first recurrence duration and operative methods,and to discuss the strategy of bladder-preserving for patients with bladder transitional cell carcinoma(TCC).Methods:A total of 249 cases of bladder tumor with complete follow-up data,treated from 1991 to 2005 in our hospital,were studied re trospectively.The correlation between overall recurrence rate,survival rate and the first recurrence duration and operative methods were analyzed by the life table method,and statistical methods,like Newman-Keuls and chi-square test.Result:The first recurrence duration was not influenced by operative methods. There was no significant difference of overall recurrence rate and short-term survival rate(3-year and 5-year)among different operative methods,the highest 10-year survival rate(77.3%)occurred in the group of transurethral resection of bladder tumor(TURB)and the lowest one(65.2%)in the group of partial cystectomy,and the difference was statistically significant.Conclusions:TURB could achieve the same short-term therapeutic effect as opening operations(partial resection of bladder or resection of bladder tumors)and the higher long-term survival rate can be obtained by TURB.
RESUMO
Objective To discuss the bladder-preserving strategy for bladder tumor.Methods Totally 249 cases of bladder tumor were studied retrospectively.The analysis of overall recurrence rate,survival rate and the first recurrence-free duration according to operative methods,drugs for therapeutic bladder perfusion,and clinical stages was carried out.Results The first recurrence-free duration was not influenced by operative methods and perfusion drugs significantly.Although the overall recurrence rate and short-term survival rate were not influenced by operative methods,but the highest 10-year survival rate(77.3%) occurred in the patients received transurethral resection of bladder tumor(TURB).The recurrence rate,3-year,5-year and 10-year survival rate of the patients applied to different perfusion drug were statistically different,with the lowest recurrence rate (28.2%) in patients applied Bacillus Calmette-Guerin(BCG) and the highest survival rate was in patients applied BCG(3-year: 100%,10-year: 81.7%).According to clinical stage,the survival rate was of no statistical difference among patients belonging to T_(is),T_a,T_1 stages,and of significant difference between T_(2-4) and the other three stages.The overall recurrence rate were not significantly different among T_(is),T_a and T_(2-4) stages.Conclusion TURB combined with BCG perfusion produces favorable prognosis for bladder tumor patients without muscle-involved,while bladder-preserving operation is not beneficial for patients with muscle-involved bladder tumor.