1.
Indian J Biochem Biophys
;
1998 Oct; 35(5): 296-302
Artigo
em Inglês
| IMSEAR
| ID: sea-26855
RESUMO
Inhibition of the activities of fatty acid synthase and ATP-citrate lyase (ATP-CL) by fatty acids and their CoA esters has been studied. Purified fatty acid binding protein from human fetal brain reverses this inhibition. This protein also activates the enzyme when added alone. ATP-citrate lyase and fatty acid synthase activity gradually increased with the advancement of gestation showing a relationship between high demand of fatty acid synthesis in developing brain and supply of its precursors.