Functionality, comorbidity, complication & surgery of hip fracture in older adults by age distribution

SUMMARY BACKGROUND Hip fractures may be the greatest complication secondary to osteoporotic disorder. The objective of this study was to determine the influence of age distribution in the functionality, comorbidity, complications and surgical features of older adults with hip fractures. METHODS A prospective cohort study was carried out from 2013 to 2014. A sample of 557 adults over 75 years old with osteoporotic hip fractures was recruited from the Orthogeriatric Unit of the León University Hospital (Spain). Age distributions of 75-84, 85-90 and >90 years old were considered. Firstly, sociodemographic data, fracture type and hospital staying days were collected. Secondly, baseline functionality (Barthel index), ambulation, cognitive impairment and comorbidities were described. Thirdly, surgical intervention, urgency, type, American Association of Anesthesiologists (ASA) scores, non-surgical cause, and baseline pharmacologic treatments were determined. Finally, complications and features at hospital discharge were observed. RESULTS The age ranges did not show any statistically-significant differences (P<.05; R2=.000-.005) for gender, fracture type, or number of hospital staying days. Statistically-significant differences (P<.05; R2=.011-.247) between age groups were observed for Barthel index, cognitive impairment, dementia, osteoporosis, Parkinson's disease, aortic stenosis, surgery type, ASA-score, non-surgical cause, benzodiazepines, antidementia, anti-osteoporosis, insulin, pharmacologic treatments, renal function alteration, heart failure, destination and ambulation features. All other measurements did not show statistically-significant differences (P>.05; R2=.000-.010). CONCLUSION Age distributions greater than 75 years old may determine the functionality, comorbidities, surgical features, baseline pharmacologic treatments, complications and features at hospital discharge for older adults who suffer a hip fracture.

RESUMO CONTEXTO As fraturas do quadril podem ser a maior complicação secundária à doença osteoporótica. O objetivo deste estudo foi determinar a influência da distribuição etária na funcionalidade, comorbidade, complicações e características cirúrgicas de idosos com fratura de quadril. MÉTODOS Um estudo prospectivo de coorte foi realizado de 2013-2014. Uma amostra de 557 adultos mais velhos, com mais de 75 anos, com fratura de quadril osteoporótica foi recrutada na Unidade Ortogeriátrica do Hospital Universitário de León (Espanha). As distribuições de idade de 75-84, 85-90 e >90 anos foram consideradas. Em primeiro lugar, foram coletados dados sociodemográficos, tipo de fratura e dias de permanência hospitalar. Em segundo lugar, foram descritas funcionalidades de base (índice Barthel), ambulação, comprometimento cognitivo e comorbidades. Em terceiro lugar, determinaram-se a intervenção cirúrgica, a urgência, o tipo, os resultados da Associação Americana de Anestesiologistas (ASA), a causa não cirúrgica e os tratamentos farmacológicos iniciais. Finalmente, foram observadas complicações e características na alta hospitalar. RESULTADOS As faixas etárias não mostraram diferenças estatisticamente significativas (P <,05; R2 = ,000-,005) para sexo, tipo de fratura ou dias de permanência hospitalar. Foram apresentadas diferenças estatisticamente significativas (P <,05; R2 = ,011-,247) para o índice de Barthel, comprometimento cognitivo, demência, osteoporose, doença de Parkinson, estenose aórtica, tipo de cirurgia, pontuação ASA, causa não cirúrgica, benzodiazepínicos, antidementia, antiosteoporose, insulina, tratamentos farmacológicos, alteração da função renal, insuficiência cardíaca, destino e características de ambulação entre grupos etários. O restante das medidas não apresentou diferença estatisticamente significativa (P> 0,05; R2 = ,000-,010). CONCLUSÃO As distribuições de idade após 75 anos podem determinar a funcionalidade, comorbidades, características cirúrgicas, tratamentos farmacológicos de base, complicações e características na alta hospitalar de adultos mais velhos que sofrem fratura de quadril.

Prevalence of Frailty in Patients with Osteoporotic Vertebral Compression Fracture and Its Association with Numbers of Fractures

PURPOSE: To assess the association between frailty and osteoporotic vertebral compression fracture (OVCF) and to evaluate the relationship between numbers of OVCFs and frailty. MATERIALS AND METHODS: We enrolled 760 subjects, including 59 patients (with OVCF) and 701 controls (without OVCF). Successful matching provided 56 patient-control pairs. We analyzed principal clinical and demographic information, which included sex, age, height, weight, body mass index (BMI), variable frailty phenotypes, and Oswestry Disability Index (ODI) and EuroQol 5-dimension questionnaire (EQ-5D) scores. The association between frailty and OVCF was ascertained. In addition, the degrees of disability and quality of life attributable to frailty were determined. RESULTS: The prevalence of frailty was significantly higher in the OVCF group than in the control group (p < 0.001). Most of the frailty phenotypes, such as exhaustion, physical inactivity, slowness, and handgrip strength, were also significantly observed in the OVCF group. Within the OVCF group, the participants with frailty had significantly higher disability and lower quality of life than those in a robust state (p < 0.001 for ODI and EQ-5D). In addition, the multivariate logistic regression analysis demonstrated that the patients with low BMI [odds ratio (OR)=0.704; 95% confidence interval (CI), 0.543–0.913] and ≥3 fractures (OR=9.213; 95% CI, 1.529–55.501) within the OVCF group were associated with higher odds of frailty. CONCLUSION: The present study showed significant relationships between frailty and OVCF, severity of symptoms, and disability induced by OVCF. Furthermore, frailty could be a causal and/or resulting factor of OVCFs.

Optimización perioperatoria del paciente anciano con fractura osteoporótica de cadera / Perioperative care of older patients with hip fractures

The number of osteoporotic fractures is increasing along with population aging. Most patients with these type of fractures are older than 65 years, with multiple chronic conditions and different degrees of disability. Hip fracture is the most relevant osteoporotic fracture due to its frequency, costs, severity and complications. Multidisciplinary management is of the utmost importance to obtain good therapeutic results. We herein review the management of this fracture. Orthogeriatric joint management should be incorporated in fragility fracture treatment. We contribute with general recommendations for the perioperative management, which can be homologated for the management of older patients with other type of fragility fractures.

Fracturas osteoporóticas de ramas pélvicas: A Benign Injury? / Fractures ostéoporotiques des branches pubiennes, est-ce qu'elles sont bénignes? / Osteoporotic Pubic Rami Fracture

Objetivo: analizar los pacientes tratados por fractura osteoporótica de ramas pélvicas en nuestro hospital. Métodos: se analizan retrospectivamente pacientes con fracturas de ramas pélvicas atendidos en el Servicio de Urgencias de nuestro hospital. Los parámetros examinados incluyen datos demográficos, diagnósticos, lesiones asociadas, comorbilidades, autonomía previa, complicaciones y mortalidad al año. Resultados: 60 pacientes (51 mujeres) con una edad media de 83,5 años (rango, 65,1-99) presentaron fractura osteoporótica de ramas pélvicas; 6 pacientes presentaban antecedentes de fractura de ramas pélvicas y 23 de fractura osteoporótica de otra localización. En 27 casos se asociaban a lesiones en otras localizaciones de la pelvis, 3 pacientes asociaban fracturas extrapélvicas y 6 traumatismos craneoencefálicos; 41 pacientes experimentaron complicaciones de algún tipo. Se requirió ingreso hospitalario en 8 casos, con una estancia media de 18 días. La mortalidad al año fue de 13,3 por ciento. Conclusiones: las fracturas osteoporóticas de ramas pélvicas afectan predominantemente a mujeres con numerosas comorbilidades. Muchas son las complicaciones descritas en estos pacientes con una mortalidad anual elevada. Es recomendable un adecuado tratamiento analgésico que permita la movilización precoz del paciente tras descartar lesiones asociadas en la pelvis(AU)

Objective: we analysed patients treated for osteoporotic rami fractures in our hospital. Methods: the records of patients were examined presenting to the emergency department with osteoporotic low-impact rami fractures. Demographic, previously ambulatory ability, diagnosis, associated injuries; comorbidity, complications, and 1-year mortality were described. Results: 60 patients (51 women) with mean age of 83,5 (range, 65,1-99) years had osteoporotic rami fracture. Six patients had previous rami fracture and 23 a osteoporotic fracture. Twenty-seven patients had other pelvic fracture associated. Three patients had other extra pelvic fracture and six had crane encephalic trauma. Forty-one patients had some kind of complication at follow up. Eight patients (13, 3 percent) were admitted to hospital with median length of stay in the hospital of 18 days. Eight (13, 3 percent) patients died within 1 year of injury. Conclusions: low-impact rami fractures affect predominantly elderly women with pre-existing comorbidities. A substantial amount of complications is described in these fractures with high annual mortality. Early rehabilitation therapy with adequate analgesic therapy is recommended(AU)

Objectif: l'objectif de cette étude est d'analyser les patients traités à cause de fractures ostéoporotiques des branches pubiennes à l'hôpital universitaire Miguel Servet, hôpital de référence du secteur 2 à Zaragoza (Espagne). Méthodes: une étude rétrospective de patients atteints de fractures des branches pubiennes, et soignés au service d'urgences de cet hôpital, a été réalisée. On a examiné des paramètres, tels que données démographiques, diagnostics, lésions associées, comorbidités, autonomie préalable, complications, et taux de mortalité par an. Résultats: soixante patients (51 femmes), dont l'âge moyen a été 83,5 ans (rang 65,1-99), souffraient de fractures ostéoporotiques des branches pubiennes ; 6 patients avaient une histoire de fractures des branches pubiennes, et 23 étaient atteints de fractures ostéoporotiques ayant une autre localisation. Dans 27 cas, les fractures étaient liées à des lésions ayant d'autres localisations du bassin, 3 patients souffraient de fractures extra-pelviennes associées, et 6 des traumatismes cranio-encéphaliques ; 41 patients ont éprouvé des complications de quelque type. Huit patients ont été hospitalisés, ayant un séjour hospitalier de 18 jours en moyenne. Le taux de mortalité par an a été 13,3 pourcent. Conclusions: les fractures ostéoporotiques pelviennes touchent souvent les femmes souffrant plusieurs comorbidités. Un grand nombre de complications se produisent chez ces patients, provoquant ainsi un haut taux de mortalité par an. Après avoir écarté la possibilité de lésions associées au niveau du bassin, il est conseillé d'appliquer un traitement analgésique permettant la mobilité précoce du patient(AU)

Fraturas osteoporóticas da coluna vertebral / Osteoporotic fractures spine

As fraturas vertebrais são comuns em idosos e em mulheres no período pós-menopausa. Tais fraturas podem ter como etiologia principal a osteoporose ou ser decorrentes de trauma, infecções ou neoplasia.A osteoporose é caracterizada por diminuição da massa e modificação da microarquitetura óssea, sendo a manifestação mais comum a fratura patológica. Apresenta como manifestação clínica dor, diminuição da altura e desalinhamento da coluna vertebral, sintomas neurológicos, bem como alteração na autoestima e problemas sociais. O diagnóstico de osteoporose é dado por meio da realização de densitometria óssea, sendo esse o padrão-ouro, podendo-se lançar mão de outros métodos de imagemem situações específicas. O tratamento da osteoporose inclui métodos para a prevenção de fraturas, tais como reposição de cálcio e vitamina D, uso de bifosfonados, paratormônio e reposição hormonal. Quando em vigência de fratura, a conduta preferida ainda é a abordagem não cirúrgica, sendo feitapor meio de imobilização, uso de analgésicos, fisioterapia e reabilitação motora. Quando em vigência de déficit neurológico, deformidade severa ou ausência de resposta ao tratamento conservador, está indicada a abordagem cirúrgica.

Vertebral fractures are common in the elderly and in women in the post menopausal period. Such fractures can have as cause osteoporosis or be due to trauma, infection or neoplasia. Osteoporosis is characterized by decreased bone mass and modified microarchitecture, the most common manifestation of a pathological fracture. Presenting clinical manifestation as pain, height loss and misalignment of the spine, neurological symptoms, and change in self-esteem and social problems. The diagnosis of osteoporosis is given by bone densitometry, this being the gold standard, and we can make use of other imaging methods in specific situations. Treatment of osteoporosis includes methods for the prevention of fractures, such as treatment with calcium and vitamin D, use of bisphosphonates, parathyroid hormone and hormone replacement. When in the presence of fracture, the preferred approach is still nonsurgical approach being taken by immobilization, analgesics, physical therapy and motor rehabilitation. Whenin the presence of neurologic deficit, severe deformity or lack of response to conservative treatment require surgical approach.