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1.
Acta Pharmaceutica Sinica ; (12): 1667-1670, 2012.
Artigo em Chinês | WPRIM | ID: wpr-274606

RESUMO

A method was evaluated for determination of twenty-one doping (including nandrolone, boldenone and methandienone) in human urine by gas chromatography-high resolution mass spectrometry. Samples were prepared by liquid-liquid extraction, concentrated, TMS derivatization and limit of detection at ng x mL(-1) by MID/GC/HRMS. According to the code of the World Anti-Doping Agency (WADA), precision and recoveries of the procedure were evaluated by replicate analysis (n = 6), the recoveries in the range of 66%-103%, with the RSD below 10.0%. The precision within the day of the method with three different concentrations was also determined RSD were less than 9.5%, 10.0% and 9.7%.


Assuntos
Humanos , Anabolizantes , Urina , Dopagem Esportivo , Cromatografia Gasosa-Espectrometria de Massas , Metandrostenolona , Urina , Nandrolona , Urina , Detecção do Abuso de Substâncias , Métodos , Testosterona , Urina
3.
Bangladesh Med Res Counc Bull ; 1978 Jun; 4(1): 32-7
Artigo em Inglês | IMSEAR | ID: sea-378

RESUMO

The influence of anabolic steroid on the process of production of rickets in vitamin-D deficient animals as well as its influence on healing of rickets with vitamin-D therapy was studied. Long-Evans strains of female rats of two age groups (6 weeks and 4 weeks) were given rachitogenic diet and were divided into five sub-groups-(I) control receiving vitamin-D from the 1st day, (II) rachitic group, (III) receiving vitamin-D from 36th day, (IV) receiving anabolic hormone from the beginning of the experiment and (V) receiving both vitamin-D and anabolic hormone from 36th day of treatment. It was observed grossly as well as histologically and radiographically that: (1) the anabolic steroid minimizes the rachitic changes in the bones of vitamin-D deficient rats, (2) in rachitic animals, a combination therapy of anabolic hormone and vitamin-D results in comparatively greater calcification of osteoid matrix and better healing and remodelling of bone than with vitamin-D alone.


Assuntos
Animais , Quimioterapia Combinada , Epífises/patologia , Feminino , Metandrostenolona/uso terapêutico , Ratos , Raquitismo/tratamento farmacológico , Tíbia/patologia , Vitamina D/uso terapêutico
5.
J Indian Med Assoc ; 1976 May; 66(9): 202-3
Artigo em Inglês | IMSEAR | ID: sea-97191
8.
Indian J Pediatr ; 1973 Dec; 40(311): 439-41
Artigo em Inglês | IMSEAR | ID: sea-81717
10.
Arch. argent. pediatr ; 68(5): 171-176, 1970 Jul. tab
Artigo em Espanhol | BINACIS, LILACS | ID: biblio-1159884

RESUMO

Se presenta un paciente de seis años de edad, afectado de anemia hipoplástica congénita. Se efectúa un análisis de la etiopatogenia, diagnóstico, pronóstico y de las posibilidades terapéuticas.


Assuntos
Humanos , Masculino , Criança , Anemia Aplástica/diagnóstico , Anemia Aplástica/etiologia , Anemia Aplástica/tratamento farmacológico , Anemia Aplástica/sangue , Ciclofosfamida/uso terapêutico , Metandrostenolona/uso terapêutico
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