Mixofibrosarcoma de bajo grado: reporte de caso / Low grade mixofibrosarcoma: case report

El mixofibrosarcoma es un subtipo de sarcoma que comúnmente se presenta en las extremidades de personas ancianas. La presentación clínica no es característica y el aspecto histológico es altamente heterogéneo, lo que frecuentemente retrasa el diagnóstico o conduce a uno equivocado. Técnicas de histoquímica e inmunohistoquímica son mandatorias para establecer el diagnóstico de MFS. Presentamos el caso de un hombre de 57 años para ilustrar lo poco sugerente de este diagnóstico dada la presentación clínica. El manejo de este tumor es con cirugía, eventualmente radioterapia y seguimiento estricto.

Myxofibrosarcoma is a subtype of sarcoma commonly found in the extremities of elderly people. The clinical presentation is not characteristic and the histological aspect is highly heterogeneous, which often delays the diagnosis or leads to the wrong one. Histochemistry and immunohistochemistry techniques are required to establish the diagnosis of SFM. We present the case of a 57-year-old man to illustrate the unimpressive nature of this diagnosis given the clinical presentation. The management of this tumor is with surgery, eventually radiotherapy and strict follow-up.

Myxoid Chondrosarcoma of the Sinonasal Cavity in a Child: a Case Report

Chondrosarcomas are malignant tumors of cartilage that rarely involve the sinonasal region, and myxoid chondrosarcoma is a rare histologic variant of chondrosarcoma that usually occurs in the soft tissue of extremities. Although several case reports and results of small series of chondrosarcomas in the sinonasal region in children are available, myxoid type chondrosarcoma is extremely rare. We recently experienced a case of low grade myxoid chondrosarcoma involving the sinonasal cavity in a 10-year-old boy, and here we report its radiologic-pathologic findings. In this case, chondroid calcification on CT and septal and marginal enhancement on MRI suggested a chondrosarcoma. Whole body PET-CT demonstrated no definite metastatic lesion and a low peak standardized uptake value primary tumor. However, no definite distinguishing imaging features were observed that distinguished low grade myxoid chondrosarcoma from conventional chondrosarcoma.

Giant Cell Malignant Fibrous Histiocytoma of the Breast: A Case Report

A case of primary malignant fibrous histiocytoma of the breast is reported. The patient was a 48-yr-old woman with a huge tumor involving almost the entire left breast. The central portion of her left breast was already rotted by extensive necrosis and inflammation. She was treated by radical mastectomy and axillary lymphadenectomy to level I. Pathologic examination supported by an immunohistochemical staining confirmed the tumor as malignant fibrous histiocytoma of giant cell type. Axillary lymph nodes were free from tumor metastasis. She had not taken any postoperative adjuvant therapy. The metastasis to lungs was found 2 months after the operation, and she died within 6 months.

Primary Intracranial Myxoid Chondrosarcoma: Report of a Case and Review of the Literature

The authors present a case of primary intracranial extraosseous myxoid chondrosarcoma without any attachment to the cranium or the meninges. The clinical and radiological findings of the primary intraparenchymal tumor are described with a review of the literature concerning cranial and intracranial myxoid chondrosarcoma.

Mixosarcoma de aurícula izquierda: presentación de un caso / Myxosarcoma of left atrium: a report of a case

El mixiosarcoma del corazón es un tumor extremadamente raro, representa menos de 1 por ciento de los sarcomas malignos. El mixoma es el tumor más frecuente del corazón y, en 90 por ciento de los casos de una mujer de 25 años de edad que inició con disnea de medianos esfuerzos, malestar general, tos productiva y edema de miembros inferiores. La telerradiografía de tórax mostró derrame pleural bilateral. El ECG indicó arritmias cardiacas y bloqueo ventricular, mientras que en el ecocardiograma se observó neoplasia maligna infiltrante a la aurícula izquierda. Se realizó toracotomía con toma de biopsia que resultó mixosarcoma. Recibió quimioterapia complementaria y actualmente se encuantra sin actividad tumoral. Se discute la frecuencia y el diagnóstico diferencial de esta enfermedad

O sinal dos -dentes flutuantes- / The floating teeth sign

Foram estudadas retrospectivamente as radiografias de oito pacientes com sinal do "dente flutuante" e encontrados os diagnósticos de ameloblastoma, granuloma eosinófilo, mixossarcoma, osteossarcoma, displasia fibrosa e cisto dentígeno (um caso cada) e dois casos de osteomielite. Säo revistas as principais causas deste sinal radiográfico