1.
In. Albala Brevis, Cecilia; Kain B., Juliana; Burrows Argote, Raquel; Díaz Bustos, Erik. Obesidad: un desafío pendiente. Santiago de Chile, Universitaria, 2000. p.69-114, ilus.
Monografia
em Espanhol
| LILACS
| ID: lil-284851
Assuntos
Humanos , Masculino , Feminino , Comportamento Alimentar/psicologia , Obesidade/etiologia , Regulação do Apetite/fisiologia , Brasil/epidemiologia , Dieta Redutora/psicologia , Estresse Psicológico/etiologia , Comportamento Alimentar , Leptina/farmacologia , Lipólise/fisiologia , Metabolismo Energético/fisiologia , Proliferadores de Peroxissomos/agonistas , Receptores Adrenérgicos beta/metabolismo , Fatores Socioeconômicos , Desacopladores/farmacologia
2.
Rev. chil. obes
;
4(3): 81-8, 1999.
Artigo
em Espanhol
| LILACS
| ID: lil-260227
RESUMO
Peroxisome proliferator-activated receptors (PPARs) are lipid-activated transcription factors that belong to the steroid/retinoic acid receptor superfamily. All their characterized target genes encode proteins that participate in lipid homeostasis. The finding that antidiabetic thiazolidinediones and adipogenic prostanoids are ligans of one of the PPARS reveals a novel signaling pathway that directly links these compounds to processes involved in glucose homeostasis and lipid metabolism including adipocyte differentiation. An understanding of this pathway could designate PPARs as targets for the development and efficient treatments for several metabolic disorders