Childhood trauma and bipolar spectrum: a population-based sample of young adults

Abstract Introduction Childhood trauma has been suggested to be involved in susceptibility to bipolar disorder (BP). However, it remains unclear whether the occurrence of childhood trauma is differently distributed in subthreshold bipolar disorder (SBP). Objective To assess childhood trauma in young adults with SBP, as compared to young adults with BP and population controls (PC). Method This was a cross-sectional, population-based study. The Mini International Neuropsychiatric Interview (MINI) was used to define the groups with BP (subjects with a lifetime or current manic episode or lifetime or current hypomania with a history of a depressive episode), SBP (subjects with a history of hypomanic episode without lifetime or current depressive episode), and subjects without mood disorders (PC). Childhood trauma was assessed using de Childhood Trauma Questionnaire (CTQ). We investigated differences regarding childhood trauma across the three groups (BP, SBP and PC). Result Except for sexual abuse, all subtypes of childhood trauma remained associated with the BP group as compared to PC. Additionally, when we compared SBP and BP, significant differences were found only for emotional abuse. No significant differences were found in relation to childhood trauma between the SBP and PC groups after adjusting for confounding factors. Conclusion These findings suggest that investigating childhood trauma, with a particular focus on emotional abuse, could be considered a preventive measure and potentially improve the prognosis.

The association between traumatic experiences and suicide attempt in patients treated at the Hospital de Pronto Socorro in Porto Alegre, Brazil

Abstract Objective To analyze associations between attempted suicide and childhood trauma. Methods A seven month comparative case-control study (28 subjects - patients with suicide attempt; 56 controls - patients without suicide attempt). The following instruments were used: Childhood Trauma Questionnaire (CTQ), Mini International Neuropsychiatric Interview (MINI), and Medical Outcomes Study (MOS). Results The group with suicide attempt had significantly higher scores for some variables: emotional abuse (p < 0.001), physical abuse (p < 0.001), emotional neglect (p < 0.001), and physical neglect (p < 0.001). Conclusions The results suggest that variables related to previous trauma may influence future suicide attempts. The adoption of preventive and therapeutic actions related to mistreatments during child development is a crucial factor in reduction of suicide risk.

Prevalência de abuso físico na infância e exposição à violência parental em uma amostra brasileira / Prevalence of physical abuse in childhood and exposure to parental violence in a Brazilian sample

O estudo objetivou avaliar a prevalência de abuso físico e exposição à violência parental na infância, segundo características sócio-demográficas. Um procedimento de amostragem de múltiplos estágios foi usado para selecionar 3.007 indivíduos de 14 anos de idade ou mais, entre 2005/2006, incluindo sujeitos de todas as regiões do país, assim, os resultados são nacionalmente representativos. Foram acessadas experiências de abuso físico (bater, bater com alguma coisa, queimar/escaldar, ameaçar/usar faca ou arma) e exposição à violência parental (testemunhou ameaça e/ou agressão física parental) na infância. Realizaram-se as análises através do teste qui-quadrado de Pearson. A prevalência de história de abuso físico na infância foi de 44,1 por cento, sendo que 33,8 por cento relataram história de abuso físico moderado e 10,3 por cento abuso físico severo. A prevalência de exposição à violência parental foi de 26,1 por cento, sendo que 7,5 por cento testemunharam violência parental moderada e 18,6 por cento testemunharam violência parental severa na infância. Análises combinadas entre estes dois tipos de violência demonstraram significativas associações entre elas. Estes resultados podem ajudar na implementação de estratégias de intervenção alertando profissionais de saúde para alta prevalência deste tipo de violência na população.

The aim of this study was to investigate the prevalence of physical abuse and exposure to parental violence during childhood, in relation to socio-demographic characteristics. Multi-stage sampling was used to select 3,007 individuals 14 years or older in 2005-2006, from all regions of the country. The study detected cases of physical abuse (beating, striking with objects, burning or scalding, threatening and/or using knives or firearms) and exposure to parental violence (witnessing parental threats and/or actual physical aggression) during childhood. Analyses were performed with the Pearson chi-square test. Prevalence of history of physical abuse in childhood was 44.1 percent (33.8 percent moderate, 10.3 percent severe). Prevalence of exposure to parental violence was 26.1 percent (7.5 percent witnessed moderate parental violence and 18.6 percent severe). Combined analyses of these two types of violence showed significant associations between them. The findings may help implement intervention strategies to call the attention of health professionals to the high prevalence of this type of violence.